Functional and morphological analysis of the main excretory duct

小鼠唾液腺主要排泄管上皮(MEDE)的超微结构和功能尚不清楚。因此，本研究的目的是用透射和扫描电子显微镜描述雄性和雌性小鼠颌下腺的超微结构。此外，还讨论了它们的功能。研究结果如下。雄鱼雌体内可见三种主要细胞：-I型和-II型细胞和基底细胞。这种方法的特点是细胞间小管的存在。I型细胞数量最多。线粒体丰富，高尔基体发达，电子透亮的含脂颗粒少，糖原颗粒多，滑面内质网丰富，基底层皱缩不发达。第二类细胞数量第二多。最具特征的是在…周围存在丰富的具有酸性磷酸酶活性的异质含脂颗粒。更可怕的是。它们可能来源于线粒体的转化。去势后颗粒数未见减少。基细胞与基膜相邻，细胞核较大，细胞器不发达。这种方法似乎参与了分泌活动，除了通过许多细胞间小管的存在而使小鼠唾液低渗性外。雌体内可见四种主要细胞：-I、II、III型和基底细胞。它们被方便地分类，与男性的不一致。该上皮不同于男性上皮，其特征是存在具有极强电子光细胞质的II型细胞。I型细胞除基底部皱褶发达外，其余均与雄性细胞相似。II型的最大特点是含有丰富的游离核糖体和带核仁的过氧化酶体。雄鱼体内未见III型细胞。由于底部褶皱的发达，这种方式似乎比男性更能进行水和离子的运输活动。较少

Ultrastructure and function of the main excretory duct epithelium (MEDE) of the mouse salivary glands remain obscure. Accordingly the purpose of this study is to describe the fine structure of the MEDE of male and female mouse submandibular glands using transmission and scanning electron microscopy. Furthermore their functions are discussed. The results are as follows.l. Three principal cells were observed in the MEDE of the male : -type-I and -II cells and basal cells. This MEDE was characterized by the presence of intercellular canaliculi. Type-I cells were the most numerous. They had abundance of mitochondria, well-developed Golgi apparatus, a few electron lucent lipidcontaining granules, many glycogen granules, abundant smooth endoplasmic reticulum (SER) and poorly developed basal infoldings. Type-II cells were the second most numerous. The most characteristic feature was the presence of abundant heterogeneous lipid-containing granules having acid phosphatase activity in the periph … More ery. They may be derived from mitochondrial transformation. The number of granules didn't decrease by castration. Basal cells were situated adjacent to the basal lamina, and had a large nucleus and poorly developed cell organelles. This MEDE seems to participate in secretory activity in addition to making the mouse saliva hypotonic by the presence of many intercellular canaliculi.2. Four principal cells were observed in the MEDE of the female : -type-I, II and III and basal cells. They were classified conveniently and didn't correspond to the male ones. This epithelium was different from the male one and characterized by the presence of the type II cell having extremely electron light cytoplasm. Type-I cells resembled the male ones except well-developed basal infoldings. The most characteristic feature of Type-II was the presence of abundant free ribosomes and peroxisomes with nucleoid. Type-III cells were not present in the male MEDE. This MEDE seems to engage in water and ion transport activity rather than male one because of well-developed basal infoldings. Less