Study on Naturally Occurring Drug Materials in Indonesia -4
Study on Naturally Occurring Drug Materials in Indonesia -4
批准号:
04041069
负责人:
KITAGAWA Isao
金额:
$5.76万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for international Scientific Research
财政年份:
1992
资助国家:
日本
项目状态:
已结题
起止时间:
1992 至 1993
中文摘要
印度尼西亚可能是世界上天然产品资源最丰富的国家之一,特别是植物资源。印尼人长期以来一直使用药用植物作为传统药物,但其中大部分尚未得到现代科学的证实。我们的研究项目名为“印尼天然药物材料研究-4”,旨在揭示天然药物材料,即药用植物,在1992年的考察中,我们首先在马鲁古省的市场上收集了有关马鲁古香料的信息。接下来,我们访问了中苏拉威西省,从当地人那里收集了大约200种传统药用植物的信息,并收集了23种药用植物进行化学调查。1993年,我们收集的所有植物都在印度尼西亚博戈尔的博戈里植物标本馆进行了植物学鉴定。此外,这些标本的酒精提取物在大坂大学进行了几次色谱分析,以分离化学成分,用于检查其生物活性。这些分析研究正在进行中。迄今为止,我们已经获得了一些有希望的证据,这表明对我们调查中收集的这些材料进行化学和生物学研究可能会导致我们发现新的具有药理学重要性的物质,与印度尼西亚生物研究和发展中心(LIPI)的合作,印度尼西亚的参与组织,今后肯定会以这种方式继续下去。
英文摘要
Indonesia is perhaps one of the richest countries in the world in natural product resources, particularly in botanical resources. Indonesian people have been using medicinal plants as traditional medicines for long time, although most of them have not yet been verified on the basis of modern science.Our research project entitled "Study on Naturally Occurring Drug Materials in Indonesia-4" aims at revealing the naturally occurring drug materials, i.e. medicinal plants, in Indonesia and anticipates the development of the academic exchange between Japan and Indonesia.In 1992 expedition, we first collected the information about Maluku spices in the market of Maluku Province. Next, we visited Central Sulawesi Province and collected information about 200 kinds of traditionally used medicinal plants from the local people and collected 23 kinds of medicinal plants for chemical investigations.In 1993, all the plants collected by us were botanically identified at Herbarium Bogoriense, Bogor, Indonesia. Furthermore, the alcoholic extracts of these specimens were subjected to several chromatographic analyses at Osaka University to isolate the chemical constituents for examination of their biological activities. Those analytical studies are in progress. We have so far obtained some promising evidence, which suggests that the chemical and biological studies of those materials collected in our survey may lead us to find new substances of pharmacological importance.The collaboration with the Research and Development Center for Biology-LIPI, Indonesia, the Indonesian participating organization, will certainly be continued in this manner hereafter.
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Hirotaka SHIBUYA: "Chemical Structures of Calotropo-sides C,D,E,F,and G.Five Additional New Oxypregnane-Oligoglycosides from the Roots of Calotropis gigantea(Asclepiadaceae)" Chemical and Pharmaceutical Bulletin. 40. 2647-2653 (1992)
Hirotaka SHIBUYA:“牛角瓜苷 C、D、E、F 和 G 的化学结构。来自牛角瓜(萝藦科)根部的另外五种新的氧孕烷低聚糖苷”化学和制药通报。
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Hirotaka SHIBUYA: "On the Constituents of the Bark of Fagara rhetza(Rutaceae).(2):Lignan Glycosides and Two Apio-glucosides" Chemical and Pharmaceutical Bulletin. 40. 2639-2642 (1992)
Hirotaka SHIBUYA:“关于 Fagara rhetza(芸香科)树皮的成分。(2):木脂素糖苷和两种 Apio-葡萄糖苷”化学和药物通报。
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Hirotaka SHIBUYA: "On the Constitents of the Bark of Fagara rhetza (Rutaceae). (1) : Alkaloids, Phenylpropanoids, and Acid Amide" Chemical and Pharmaceutical Bulletin. 40. 2325-2330 (1992)
Hirotaka SHIBUYA:“关于 Fagara rhetza(芸香科)树皮的成分。(1):生物碱、苯丙素和酰胺”化学和药物通报。
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Isao KITAGAWA: "Chemical Structures of Three New Triterpenoids, Bruceajavanin A, Dihydrobruceajavanin A, and Bruceajavanin B, and a New Alkaloid Glycoside Bruceacanthinoside, from the Stems of Bruceajavanica (Simaroubaceae)" Chemical and Pharmaceutical Bu
Isao KITAGAWA:“来自鸦胆子茎中的三种新三萜类化合物:鸦胆子素 A、二氢鸦胆子素 A 和鸦胆子素 B 以及一种新的生物碱苷鸦胆子苷的化学结构”化学和制药部
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Isao KITAGAWA: "Chemical Structures of Carotroposides A and B,Two New Oxypregnane-Oligo-glycosides from the Roots of Calotropis gigantea(Asclepiadaceae)" Chemical and Pharmaceutical Bulletin. 40. 2007-2013 (1992)
Isao KITAGAWA:“胡萝卜苷 A 和 B 的化学结构,两种来自牛角瓜(萝藦科)根部的新氧孕烷低聚糖苷”化学和药物通报。
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共 26 条
Chemical Investigation of Naturally Occurring Drug Materials. Elucidation of Scientific Basis for Traditional Medicines and Exploitation of New Naturally Occurring Drugs
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批准号:02403027
-
项目类别:Grant-in-Aid for General Scientific Research (A)
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资助金额:$23.04万
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财政年份:1990
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负责人:KITAGAWA Isao
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依托单位:
Investigation of Naturally Occurring Drug Materials in Indonesia-3
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批准号:02041054
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$6.08万
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财政年份:1990
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负责人:KITAGAWA Isao
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依托单位:
Investigation of Naturally Occurring Drug Materials in Indonesia-2
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批准号:63041083
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项目类别:Grant-in-Aid for Overseas Scientific Survey.
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资助金额:$7.36万
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财政年份:1988
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负责人:KITAGAWA Isao
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依托单位:
Search for Bioactive Marine Natural Products
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批准号:62470137
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.8万
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财政年份:1987
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负责人:KITAGAWA Isao
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依托单位:
海外基金