Short-term effect of frozen-stored disk allograft repair on the osteoarthritic sheep temporomandibular joint

目的观察冷冻保存同种异体关节盘移植对关节盘摘除术后的短期疗效。材料与方法复制绵羊双侧颞下颌关节骨性关节炎模型，3个月后行单侧关节盘切除及冷冻保存同种异体关节盘修复。供体盘取自健康兔。盘被深度冷冻，在零下70摄氏度下储存一个月，并在嫁接时解冻。健侧关节未受干扰，3个月后作为对照。术后6个月处死动物。结果所有移植盘均发生穿孔和移位。在移植关节中，髁状突表面部分剥离，部分表面呈纤维状修复。结论冷冻保存的同种异体关节盘对骨关节炎性TMJ的间置材料有一定的指征。

Aim The aim of this study is to evaluate short-term effect of frozen-stored disk allograft following diskectmy on the osteoarthritic sheep temporomandibular joints (TMJ).Materials and Methods Osteoarthritis was induced in bilateral sheep TMJ.Three months later, unilateral diskectomy and frozen-stored disk allograft repair were performed. The donor disk had been obtained from healthy aheep at sacrifice. The disk was deep-frozen and stored at-70 degrees Celsius for a month and thawed at grafting. The contralateral joints were not disturbed, being served as a control at 3 months. At 6 months after the initial procedure, the sheep were sacrificed.Results All grafted disks were perforated and displaced. In the grafted joints, condylar srticular surface was partly denuded and some part of the surface showed fibrous repair. The control joints showed osteoarthritic changes.Conclusion Frozen-stored allogenic disk has a little indication for an interpositional material in an osteoarthritic TMJ.