Development of Extra High Cross-Linkage Structured Resin without Environmental Endocrine Disruptor

我们一直致力于开发一种高性能的牙科基质树脂，而不会对环境产生内分泌干扰。我们试图利用共价键和氢键来控制交联结构，以提高树脂的力学性能。合成了由甲基丙烯酸甲酯(MAA)和甲基丙烯酸甲酯(UDMA)组成的高韧性、高强度、高刚性的高性能树脂。在卤素和氙气两种光聚合光源下，UDMA/MAA树脂的力学性能均优于由三乙二醇二甲基丙烯酸酯(TEGDMA)组成的稀释剂共聚树脂，但所有树脂的力学性能都发生了变化。UDMA/MAA树脂的特点是同时具有韧性、强度和刚性。特别是，这一特点在氙气光源中尤为显著。上述结果表明，…的机制树脂的更多热性能在很大程度上取决于整体结构以及所实现的转化率。光聚合后的热处理有效地改善了所有树脂的力学性能。这一趋势在UDMA基树脂中尤为明显。热聚合后，UDMA/MAA树脂的弯曲强度约为300 Mpa，而由TEGDMA组成的常规树脂的弯曲强度约为200 Mpa。UDMA/MAA树脂的疲劳强度、耐水性和耐磨性均优于常规树脂。因此，UDMA/MAA树脂在极高的水平上统一了所有的机械性能。此外，UDMA/MAA树脂在细胞培养上表现出与传统牙科基质树脂相似的行为。因此，UDMA/MAA树脂有可能取代由TEGDMA组成的传统牙科基质树脂作为稀释剂共聚单体，成为高性能树脂基复合材料。较少

We have been aimed at the development of a high performance dental matrix resin without the environmental endocrine disruptor. We tried to improve the mechanical properties of resins controlling the cross-linked structure using both of the covalent and hydrogen bonds. As a result, we attained to the synthesis of high performance resin, which is high toughness even with high strength and high rigidity, composed of urethane dimethacrylate (UDMA) and methacrylic acid (MAA). All the mechanical properties of UDMA/MAA resin were superior to those of conventional matrix resins composed of tri(ethylene glycol) dimethacrylate (TEGDMA) as a diluent comonomer in both of Halogen and Xenon light source for photo-polymerization though those of all resins had been changed by the light source. The feature of UDMA/MAA resin was to have had toughness simultaneously with strength and rigidity. Especially, this feature was remarkable in the Xenon light source. Above-mentioned result shows that the mechani … More cal properties of the resin are greatly dependent on the overall structure as well as with the conversion achieved. The heat-treatment after photo-polymerization has been effective to improve the mechanical properties of all resins. The tendency was especially noted in UDMA based resin. After thermo-polymerization, the flexural strength of the UDMA/MAA resin was about 300 MPa while those of the conventional resins composed of TEGDMA were about 200 MPa. The fatigue strength, water durability and wear resistance of UDMA/MAA resin were all more excellent than the conventional resin. Consequently, the UDMA/MAA resin has united all mechanical properties at an extremely high level. In addition, UDMA/MAA resin showed behavior similar to the conventional dental matrix resin on the cell culture. Therefore, UDMA/MAA resin has shown the possibility of replace the conventional dental matrix resins composed of TEGDMA as a diluent comonomer and of appear the high-performance resin based composite materials. Less