Evaluation of Bone Metabolism of Alveolar Bone beneath the Denture Base by using SPECT

本研究旨在利用SPECT揭示义齿基托骨代谢的动态变化。用戊巴比妥麻醉Wistar大鼠，拔除右上颌牙。为了观察骨代谢活动，采用伽玛照相机对大鼠颅骨进行SPECT扫描。Tc-99m-MDP （74MBq/大鼠）静脉注射。尽管SPECT图像质量低于平面骨图，但定量分析图像提供了足够的信息来检查义齿基托下牙槽骨的骨代谢活动。

This study aimed to reveal the dynamic change of bone metabolism under the denture base using SPECT. Wistar rats were anesthetized with pentobarbital and the right maxilla teeth were extracted. To observe the bone metabolic activity, SPECT of rat cranium was taken using a gamma-camera. Tc-99m-MDP (74MBq/rat) was injected intravenously. Although the SPECT images were lower quality than planer bone scitigram, quantitative analysis of the the images provided sufficient information to examine the bone metabolic activity of alveolar bone beneath the denture base.