Molecular mechanisms for heat stress-associated skeletal muscle hypertrophy-a possible application of heat stress to sports sciences-

本研究旨在探讨热应激相关骨骼肌肥厚的分子机制，并探讨有效、安全的运动方式，以增加肌肉体积，以及对抗衰老相关肌肉萎缩（骨骼肌减少症）的对策。有证据表明，应激反应在骨骼肌肥大中起关键作用。热应激可能是一个有用的工具，不仅是肌肉量的增加，而且在运动损伤后的康复。

The purpose of this study was to investigate the molecular mechanisms for heat stress-associated skeletal muscle hypertrophy, and to develop effective and safe physical exercise for a gaining of muscle volume as well as the countermeasure for aging-associated muscle atrophy(sarcopenia). Evidences suggested that stress response plays a key role in skeletal muscle hypertrophy. Heat stress may be a useful tool for not only a gaining of muscle volume but also rehabilitation after sports injuries.