Development of focused charged-particle beam optics based on charge-up of insulator capillaries

我们已经开发出一种方法来提供微米或纳米尺寸的量子光束。该方法采用锥形玻璃毛细管，其长度为几厘米，出口直径从亚微米到100微米的数量级，以实现对辐照样品的聚焦。对于keV能量的高电荷态离子束，已经实现了几个1,000 cps的提取微束的强度。对于MeV能量的光束，一些生物活体靶，如HeLa细胞，大肠杆菌，和青鳉胚胎已被照射的玻璃毛细管作为一个独特的工具，微米级的修改。

We have developed a method to provide micro- or nano-meter sized quantum beams. The method employs tapered glass capillaries whose length is several cm and outlet diameter is of the order from sub-micron to 100 micron to realize the focusing on the irradiated samples. For keV-energy highly charged ion beams, the intensity of the extracted microbeam of several 1,000 cps has been achieved. For MeV-energy beams, some biological living targets such as HeLa cells, Escherichia coli, and Medaka embryos have been irradiated with the glass capillaries as a unique tool for micron order modification.