The influence that vasopressin gives a blood vessel wall cell
The influence that vasopressin gives a blood vessel wall cell
批准号:
20791327
负责人:
MUKOYAMA Takeo
金额:
$1.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
培养人脐血管内皮细胞,对照组和单纯用脂多糖刺激培养的脂多糖刺激,分为加压素组和加压素组。培养结束后检测IL-6、IL-8蛋白密度。结果表明,后叶加压素刺激可使IL-6、IL-8升高,而内毒素刺激可增强IL-6、IL-8的表达。对于加压素,提出了参与炎症反应通过细胞壁细胞因子的可能性。
英文摘要
I cultured a human umbilical vascular endothelial cells and I stimulated it in control group and LPS which I cultured only by LPS stimulation afterwards and classified it in vasopressin and mixture vasopressin group which I cultured. I measured IL-6, the protein density of IL-8 after the culture end. As a result, IL-6, IL-8 increased by vasopressin stimulation, and what was reinforced by lipopolysaccharide stimulation became clear. As for vasopressin, the possibility that participated in inflammation reaction to go through cytokine of a cell wall cell was suggested.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kinoshita K, Sakurai A, Mukoyama T, Noda A, Kogawa R, Yamaguchi J, Azuhata T, Utagawa A, Moriya T, Tanjoh K]
通讯作者:
Tanjoh K
DOI:
10.1016/j.resuscitation.2009.04.005
发表时间:
2009-07-01
期刊:
RESUSCITATION
影响因子:
6.5
作者:
[Mukoyama, Takeo, Kinoshita, Kosaku, Tanjoh, Katsuhisa]
通讯作者:
Tanjoh, Katsuhisa
海外基金