The neural basis of delusional misidentification in dementia with Lewy bodies

在路易体痴呆(DLB)中，妄想的患病率高于任何其他痴呆症。主成分分析表明，错别性妄想与内容特异性妄想如妄想盗窃或妄想嫉妒相互关联，阿尔茨海默病伴皮质下缺血性血管病变患者的妄想率明显高于不伴皮质下缺血性病变的阿尔茨海默病患者。这一结果提示皮质下缺血性血管病变可能是退行性痴呆妄想发生的危险因素。

In dementia with Lewy bodies (DLB) the prevalence of delusion was higher than that in any other dementia. The principal component analysis for all kinds of delusion in DLB revealed that misidentificational delusion and contents specific delusion such as delusional theft or delusional jealousy might related reciprocally.Furthermore, Alzheimer's disease patients with subcortical ischemic vascular lesionswere significantly more delusional than those without. This result suggests thatsubcortical ischemic vascular lesions may be considered as a risk factor for thedevelopment of delusions in degenerative dementia.