Analysis of cardiac viability after myocardial ischemia and infarction.

本研究描述了在心肌间质间隙中发现的透析液心脏标记物和神经递质水平的测量。使用这种心脏微透析技术，肌红蛋白，作为心肌蛋白质之一，释放诱发的地昔帕明（细胞损伤诱导药物）被检测为心脏活力的指标。该指数随缺血时间延长而降低。缺血预处理增强心脏存活力的保护。该系统为监测心肌缺血/梗死后的心脏活力提供了新的可能性。

The present study describes a measurement of the dialysate cardiac marker and neurotranmitter levels found in the myocardial interstitial space. Using this cardiac microdialysis technique, myoglobin, as one of the cardiac muscle proteins, release evoked by the desipramine(cell injury-induced drug) was detected as an index of cardiac viability. This index decreased in proportion to the ischemia time. Ischemic preconditioning enhances preservation in cardiac viability. This system offers a new possibility for monitoring cardiac viability after cardiac ischemia/infarction.