Influence of physical agents on peripheral nerve regeneration and skin lesion after transection of the mouse sciatic nerve.

在周围神经再生完成之前，保护肌肉和皮肤的性质不退化是最重要的事情之一。为评价物理制剂对周围神经再生的影响，本研究探讨了电刺激、超声等物理制剂促进再生神经纤维成熟的环境，建立了小鼠高强度机械负荷压疮模型，该模型可用于研究物理制剂对创面愈合的影响。此外，我们还展示了超声波可能是加速皮肤损伤和再生神经的形态和功能重建的有用工具。

To preserve property of the muscle and skin from degeneration is one of the most important things until peripheral nerve regeneration was completed. In this study, to evaluate the effective of physical agents on peripheral nerve regeneration, we investigate that physical agents, such as electrical stimulation, ultrasound, promoted the environment to be suitable for mature of regenerating nerve fiber.This study demonstrates that the development of mouse model of pressure ulcer by intensive mechanical loads, and this model was adequate to study the effects of physical agents on wound healing. In addition, we were able to show that ultra sound might be useful tools to accelerate morphological and functional reconstruction on skin lesion and regenerating nerve