The study for solution of rupture and glowing of cerebral aneurysms using the novel flow simulation methods with MRI

背景：颅内动脉瘤的血流动力学被认为在其生长和破裂中起着重要作用。通常基于三维(3D)CT血管成像的计算流体动力学(CFD)需要一个耗时的分析过程。基于磁共振图像的磁共振流体动力学(MRFD)是一种分析流动动力学的新工具，也是一种更容易获得此类信息的有前途的方法。方法：对15例患者的15个动脉瘤进行了MRI和3D-CT血管成像检查，其中2个动脉瘤破裂。从图像重建中提取MRFD和CFD的流动数据、三维流线、流速分布和壁面切应力(WSS)，并进行比较。结果：两种流动动力学图像显示的三维流型和WSS图非常相似。然而，最大WSS的计算值相差很大，没有显著的相关性。此外，在1例破裂的病例中，CFD显示的评价动脉瘤内血流的可视化程度较低。

BACKGROUND : Hemodynamics in intracranial aneurysms is thought to play an important role in their growth and rupture. Usual computed fluid dynamics(CFD) based on three-dimensional(3D) computed tomographic(CT) angiography requires a time-consuming process for analysis. Magnetic resonance fluid dynamics(MRFD) based on MR images is a new tool for analyzing flow dynamics and a promising method for obtaining such information more easily. We compared the data from MRFD and CFD and studied the clinical feasibility of MRFD.METHODS : A total of15aneurysms, including two ruptured ones, in15patients were investigated with MR imaging and 3D-CT angiography. The flow data of MRFD and CFD, 3D stream lines, flow velocity profile and wall shear stress(WSS) were extracted from the image reconstruction and were compared each other.RESULTS : Both flow dynamics images showed quite similar 3D flow pattern and WSS map. However, the calculated value of maximum WSS was quite different and there was no significant correlation. Further, in one ruptured case, CFD showed less visualization to evaluate the intra-aneurysmal flow.