Basic science technology study of new revision total hip arthroplasty using a fusion protein and the nanowire processing
Basic science technology study of new revision total hip arthroplasty using a fusion protein and the nanowire processing
批准号:
21591923
负责人:
NARUSE Kouji
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
在这项研究中,我们的目的是开发一种新的重建技术,用于在翻修和二次翻修全髋关节置换术中发生的广泛的骨缺损。我们努力显著改善目前基于现有同种异体骨移植的关节功能恢复技术。利用激素-胶原结合域和生长因子制备假体复合材料。胶原蛋白结合域作为分子生物学的工具,以及金属。镀纳米线加工技术作为医学工程工具。我们的研究显示碱性成纤维细胞生长因子。胶原结合域的研究对新技术的发展具有重要意义。
英文摘要
In this study we aimed to develop a new reconstruction technique for widespread bone defects that occur during revision and second revision total hip arthroplasty. We strived to significantly improve joint function restoration techniques that are currently based on existing bone allograft. prosthesis composite materials by using hormone-collagen binding domain and growth factor. collagen binding domain as molecular biological tools, as well as metal. plated nanowire processing technology as a medical engineering tool. Our study revealed that basic fibroblast growth factors. collagen binding domain were useful in the development of the new reconstruction technique.
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Abnormal tibial torsion may cause an earliest detectable deformity in STR Ort Crlj osteoarthritis mouse model
异常胫骨扭转可能导致 STR Ort Crlj 骨关节炎小鼠模型最早可检测到的畸形
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Naruse, K., et. al.]
通讯作者:
et. al.
各種創傷被覆剤における低出力超音波パルスの超音波透過への影響
低功率超声脉冲对各种伤口敷料中超声传输的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hijioka H, et al, 成瀬康治]
通讯作者:
成瀬康治
Inactivity but Not ovariectomy Determines the mechanical property and Quality of Bone in the Hind Limbs of Aged Female Rats
不活动而非卵巢切除决定老年雌性大鼠后肢骨的机械特性和质量
DOI:
--
发表时间:
2011
期刊:
Kitasto Medical Journal
影响因子:
--
作者:
[Suto Mitsutoshi, Kouji Naruse]
通讯作者:
Kouji Naruse
DOI:
10.1007/s00198-009-0888-z
发表时间:
2009-11-01
期刊:
OSTEOPOROSIS INTERNATIONAL
影响因子:
4
作者:
[Matsumoto, Y., Mikuni-Takagaki, Y., Sakurai, T.]
通讯作者:
Sakurai, T.
Low-intensity pulsed ultrasound promotes the osteogenic effectinduced by bone allograft
低强度脉冲超声促进同种异体骨移植的成骨作用
DOI:
--
发表时间:
2011
期刊:
Kitasato Med J
影响因子:
--
作者:
[Aikawa J,Naruse K,Uchida K,Katano M, Mikuni-Takagaki Y, Kozai Y, Kashima I, Takaso M,ltoman M,Urabe K]
通讯作者:
Takaso M,ltoman M,Urabe K
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