Response of irradiated tissue supporting implant prosthesis under the compressing force.

这项研究的目的是估计受照射的组织对加压压力的反应。照射后直接加压小鼠成骨样细胞，检测细胞凋亡通道基因表达。半胱氨酸天冬氨酸氨基转移酶的活性随辐射强度的增加而显著增加，随压力的增加而降低。人们认识到，在压力作用下，与防止细胞凋亡相关的基因表达增加。

The aim of this study was to estimate the response of the irradiated tissue added the compressing force. Mouse osteoblast-like cells were compressed directly after the irradiation, gene expression of apoptosis channel was examined. Activation of caspase significant increased with stronger radiation, and decreased with the compressed force. It was recognized that gene expression related to prevention of apoptosis were increased under the compressing force.