The influence of coaggregation for a volatile sulfide production of Fusobacterium

本研究的目的是阐明牙周病原菌核梭杆菌与其他微生物共聚集对核梭杆菌产生挥发性硫化物(VSC)的影响。观察到核盘藻与牙龈卟啉单胞菌之间的共聚集反应，结果表明，与单独孵育核盘藻相比，与活菌孵育相比，核盘藻VSC的产生显著增加。与活菌共同孵育后，与VSC产生相关的核盘菌酶的基因表达有增强趋势，而与热灭活微生物或菌液上清液共同孵育则无明显影响。

The aim of this study was to clarify the influence of coaggregation between Fusobacterium nucleatum, a periodont pathogenic bacteria, and other microorganisms for production of volatile sulfur compound (VSC) by F. nucleatum. The coaggregation reaction was observed between F. nucleatum and Porphyromonas gingivalis, and shown that the production of VSC was significantly enhanced by incubation with live P. gingivalis compared to incubation F. nucleatum solely. It was also observed that the gene expression of F. nucleatum enzyme related with VSC production was tended to be enhanced by incubation with live P.gingivalis together whereas no effect was shown when incubated with heat-killed microorganism or supernatant of medium of P.gingivalis.