Novel functional linkages of drinking・feeding behavior and TRP channels: Clarification by the post-genome approach
Novel functional linkages of drinking・feeding behavior and TRP channels: Clarification by the post-genome approach
批准号:
22390044
负责人:
UETA Yoichi
金额:
$11.98万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
本研究的目的是利用TRPV1和TRPV4基因敲除小鼠,并与野生型小鼠的进食和饮水行为进行比较,以探讨Trp通道在渗透压感受器中的作用。我们发现TRPV1和TRPV4通道与饮酒行为和缺水后的水和食物摄入有关。
英文摘要
The purpose of the study was to investigate the roleof TRP channels known as osmotic sensors, using TRPV1 and TRPV4 knockout mice in comparison with wild type concerning about the feeding and drinking behavior. We revealed that TRPV1 and TRPV4 channels concerned drinking behavior and water and food intake after water deprivation.
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Induction of Fos expression in the rat forebrain after intragastric administration of monosodium L-glutamate, glucose and NaCl
L-谷氨酸钠、葡萄糖和氯化钠灌胃后诱导大鼠前脑 Fos 表达
DOI:
--
发表时间:
2011
期刊:
Neuroscience
影响因子:
3.3
作者:
[Otsubo, H., Kondoh, T., Shibata, M., Ueta, Y., Torii, K.]
通讯作者:
K.
バゾプレッシン産生ニューロンにおけるプリン作動性受容体とバネキシンチャネル: 電気生理学的検討
产生加压素的神经元中的嘌呤能受体和万能蛋白通道:一项电生理学研究
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[大淵 豊明, 横山 徹, 齋藤 健, 藤原広明, 上田陽一]
通讯作者:
上田陽一
Fluorescent visualization of vasopressin and oxytocin neurons in the hypothalamus and their terminals in the hypothalalnus in transgenic rats
转基因大鼠下丘脑中加压素和催产素神经元及其末端的荧光可视化
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ueta, Y]
通讯作者:
Y
DOI:
10.1016/j.peptides.2010.08.010
发表时间:
2010-11-01
期刊:
PEPTIDES
影响因子:
3
作者:
[Maruyama, Takashi, Ohbuchi, Toyoaki, Ueta, Yoichi]
通讯作者:
Ueta, Yoichi
Effects of kainic acid on arginine vasopressin (AVP) synthesis in vivo and an isolated AVP neuron in vitro
红藻氨酸对体内精氨酸加压素 (AVP) 合成和体外分离的 AVP 神经元的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Ueta, Y. Iwanaga, M. Ohkubo, J]
通讯作者:
J
共 40 条
Discovery of novel osomo-/mechano-sensing molecules and physiological function
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批准号:25293055
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.98万
-
财政年份:2013
-
负责人:UETA Yoichi
-
依托单位:
Challenge to reveal a novel role of central vasopressin and oxytocin neurons by optogenetic approach
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批准号:23659127
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
-
财政年份:2011
-
负责人:UETA Yoichi
-
依托单位:
Novel roles of neurohypophyseal hormones and biological active substances on brain function in genetic animal model
-
批准号:16390061
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.47万
-
财政年份:2004
-
负责人:UETA Yoichi
-
依托单位:
The localization and physiological role of adrenomedullin and related-peptides in the central nervous system
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批准号:10218210
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$30.21万
-
财政年份:2002
-
负责人:UETA Yoichi
-
依托单位:
Novel feeding-related peptides and stress reaction -Molecular based study and physiological investigation-
-
批准号:14370026
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.9万
-
财政年份:2002
-
负责人:UETA Yoichi
-
依托单位:
A role of NO on neuroendocrine system : molecular, pharmacological and neurophysiological approaches
-
批准号:11670078
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1999
-
负责人:UETA Yoichi
-
依托单位:
海外基金