Molecular mechanisms of permeability transition revealed using yeast mitochondria

线粒体通透性转变触发了随后的细胞凋亡步骤。为了了解通透性转换的分子机制，我们在本研究中利用酵母线粒体鉴定了通透性转换的调控基因。因此，我们在以前的报道中揭示了可能参与通透性转换的调控基因并不主要调节通透性转换。

Mitochondrial permeability transition triggers subsequent steps of apoptosis. To understand the molecular mechanisms of permeability transition, we in this research accessed to identify the regulatory genes for permeability transition using yeast mitochondria. As a result, we revealed that possible regulatory genes involved in permeability transition in previous reports did not mainly regulate permeability transition.