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Development of new treatment in replantation of teeth used at hyperbaric oxygen therapy

Development of new treatment in replantation of teeth used at hyperbaric oxygen therapy
高压氧治疗牙齿再植新疗法的开发
批准号：
22592143
负责人：
TAKAHASHI Toshiyuki
金额：
$2.83万
依托单位：
Tokyo Medical and Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2012
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592143/
关键词：
高気圧酸素治療歯牙再植再植スポーツ歯学外傷ラット高気圧酸素療法抜歯創傷治癒

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中文摘要
翻译
本研究旨在探讨高压氧(HBO)对大鼠再植磨牙愈合的影响。第一组大鼠接受高压氧治疗，第二组大鼠不接受任何治疗。第2组大鼠从手术当天开始给予高压氧(100%氧气，2.5大气压绝对)，每天120分钟，连续5天。两组动物均于术后7d取出实验组织。组织学评价显示，高压氧治疗可增加再植磨牙牙周组织中的微血管密度和成纤维细胞的数量。提示高压氧治疗对大鼠再植磨牙的愈合有积极作用。
英文摘要
The aim of the present study was to investigate the effect of hyperbaric oxygen (HBO) on the healing of the replanted molar in rat. Group 1 consisted of rats which underwent HBO, and Group 2 consisted of rats receiving no treatment. Group2 rats were given HBO (100% oxygen at 2.5 atmosphere absolute) for 120 minutes per day for five days, beginning the day of surgery. The experimental tissues in both groups were removed at 7 day after operation. By histological evaluation, the HBO therapy seemed to increased microvessel density and fibroblast in periodontal tissues of replanted molar. It was suggested that HBO therapy has a positive effects on the healing of the replantedmolar in rat.
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