Evaluation of the diagnostic value of 3T-MRI intratympanic injection of GBCA for Menieres disease

目的探讨Menieres病(MD)鼓室内注射GBCA后3T磁共振、甘油试验与皮层脑电的关系。共有20名MD患者接受了评估。通过鼓膜注射将稀释的加多二胺(一种基于Gd的造影剂)注入双侧鼓室。24 h后，用3.0T磁共振扫描仪对内淋巴积水进行评估。对所有患者进行甘油试验和皮层脑电地形图检查，以了解耳蜗水的情况。结果：甘油试验阳性11例(55%)，ECoG阳性12例(60%)。同时使用甘油试验和皮层脑电地形图对同一患者进行评估时，阳性结果的发生率增加到75%。20例患者中19例(95%)3T MRI检查阳性。

To investigate the relationship between 3T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Menieres disease (MD). A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients. As a esults a positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3T MRI.