A study on symbiosis between humanity and infectious diseases
A study on symbiosis between humanity and infectious diseases
批准号:
23659354
负责人:
YAMAMOTO Taro
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
本研究着眼于病毒作为病原体的适应过程和人类作为宿主的适应过程。近年来,由于全球人口的增长、城市化、热带雨林的丧失和生态系统的破坏,新型病毒进入人类社会的机会增加了。然而,从生态学的角度来看,病毒感染随着人类社会的变迁而出现和消失。我们用流行病学模拟的方法研究了这种情况。因此,我们可以得出一个假设,即人类应该与病毒共存,并将它们的毒性定为低毒力。但另一方面,我们意识到,对于我们人类来说,解决这个问题似乎是一个挑战。
英文摘要
This study focuses on adaptation process of virus as a pathogen and humanity as a host. The opportunity for a new virus to emerge into a human society, recently, increases because of the growth of global population, urbanization, the loss of rain forest and destruction of ecosystem resulted by them. However, from ecological view point, the virus infections have appeared and disappeared as a human society changes over time. We examined such a situation by using epidemiological simulation. As a result, we could obtain a hypothesis that humanity should co-live with viruses, timing them as to be a low virulent one. But in the other hand, we realized that there seems a challenge ahead for us human to address this issue.
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DOI:
10.1371/journal.pone.0048258
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Oki M, Yamamoto T]
通讯作者:
Yamamoto T
Optimal timing of insecticide fogging to minimize dengue incidence: modeling dengue transmission among various seasonalities and transmission intensities.
杀虫剂雾化的最佳时机可最大限度地减少登革热发病率:对不同季节和传播强度之间的登革热传播进行建模。
DOI:
--
发表时间:
2011
期刊:
PLoS Neglect Trop Dis
影响因子:
--
作者:
[Oki M, Sunahara T, Hashizume M, Yamamoto T.]
通讯作者:
Yamamoto T.
DOI:
10.1111/j.1348-0421.2012.12005.x
发表时间:
2013-01-01
期刊:
MICROBIOLOGY AND IMMUNOLOGY
影响因子:
2.6
作者:
[Osada-Oka, Mayuko, Tateishi, Yoshitaka, Matsumoto, Sohkichi]
通讯作者:
Matsumoto, Sohkichi
DOI:
10.4269/ajtmh.12-0456
发表时间:
2013-04
期刊:
The American journal of tropical medicine and hygiene
影响因子:
--
作者:
[Haque U, Glass GE, Bomblies A, Hashizume M, Mitra D, Noman N, Haque W, Kabir MM, Yamamoto T, Overgaard HJ]
通讯作者:
Overgaard HJ
感染症と文明-共生への道
传染病与文明——共存之路
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Umezawa M, Tainaka H, Kawashima N, Shimizu M, Takeda K, 小原克彦・田原康玄・伊賀瀬道也・三木哲郎, 山本太郎]
通讯作者:
山本太郎
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财政年份:2008
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负责人:YAMAMOTO Taro
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依托单位:
海外基金