Synkinetic movement of the vocal fold in unilaterally paralyzed larynx
Synkinetic movement of the vocal fold in unilaterally paralyzed larynx
批准号:
23659798
负责人:
YUMOTO Eiji
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
动物分为去神经支配(DNV)组和再神经支配(缝合线)组。DNV动物没有声带运动。缝合组部分动物出现联合运动,组内部分动物呼吸时出现微弱的生理运动。前者在吸入时肌电图上TA的恢复大于PCA,而后者在大多数亚组中吸入时PCA的恢复大于TA。缝线组神经纤维可能发生异常再生,导致视误导程度不同的VF联动。肌球蛋白重链IIA型的出现与联胞作用的存在无关。缝线组给予钙通道抑制剂,可促进再生过程中轴突的伸展,但未导致联动性的减少。
英文摘要
Two animal groups were made: denervation (DNV) and reinnervation (Suture) groups. DNV animals did not show vocal fold movement. Some of Suture group animals showed synkinesis and others in the group showed weak physiological movement during respiration. Greater electromyographic recruitment of TA than PCA was seen during inhalation in the former, while recruitment of PCA was greater than TA during inhalation in majority of the latter subgroup.Aberrant regeneration of nerve fibers in Suture group may have occurred, resulting in synkinesis of the VF depending on the degree of misdirection. Appearance of myosin heavy chain type IIA was not associated with the presence of synkinesis. Administration of Ca channel inhibitor, which facilitates axonal extension during regeneration, in Suture group did not result in decrease of synkinesis.
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喉頭筋電図を用いた神経過誤支配の検討
使用喉肌电图检查神经功能障碍
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Morimoto Takeshi, Kanda Hiroyuki, Miyoshi Tomomitsu, LohmannT.K.FujikadoTakashi, 讃岐徹治]
通讯作者:
讃岐徹治
喉頭筋電図による一側喉頭麻痺に対する神経再建術の術前後評価.
使用喉肌电图评估单侧喉麻痹神经重建的术前和术后。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[本間明宏, 他, 讃岐徹治]
通讯作者:
讃岐徹治
Over-adduction of the unaffected vocal fold during phonation in the unilaterally paralyzed larynx.
单侧麻痹的喉部发声时未受影响的声带过度内收。
DOI:
10.3109/00016489.2014.886020
发表时间:
2014
期刊:
Acta Otolaryngologica
影响因子:
--
作者:
[Yumoto E, Sanuki T, Minoda R, Kumai Y, Nishimoto K, Kodama N]
通讯作者:
Kodama N
Animal Model for RecurrentLaryngeal Nerve Synkinetic Reinnervationwith Immobile Vocal Fold Using SiliconTube
使用硅管固定声带进行喉返神经联动再神经支配的动物模型
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[山岸麗子, 相原一, 新家眞, 坪田一男, Kumai Y]
通讯作者:
Kumai Y
Electromyography findings in nerve-muscle pedicle implantation with arytenoid adduction for unilateral vocal fold paralysis
神经肌肉蒂植入杓状腱内收治疗单侧声带麻痹的肌电图表现
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[穂積健太, 遠藤高生, 広田雅和, 神田寛行, 森本壮, 不二門尚, 西田幸二, Sanuki T]
通讯作者:
Sanuki T
共 33 条
Basic and clinical research for surgical treatment of unilaterallaryngeal paralysis aiming at reinnervation of the laryngeal muscle
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批准号:22390316
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.57万
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财政年份:2010
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负责人:YUMOTO Eiji
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依托单位:
Basic study regarding reinnervation after recurrent laryngeal nerve paralysis
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批准号:19390435
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.32万
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财政年份:2007
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负责人:YUMOTO Eiji
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依托单位:
Effect of neurotrophic factors on regeneration of denervated recurrent laryngeal nerve
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批准号:14370547
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.42万
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财政年份:2002
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负责人:YUMOTO Eiji
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依托单位:
Experimental study for quantification of traveling mucosal wave of the vocal fold
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批准号:10671597
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1998
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负责人:YUMOTO Eiji
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依托单位:
声帯粘膜波状運動に関する実験的研究
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批准号:07671862
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:YUMOTO Eiji
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依托单位:
Vocal fold vibration viewed from tracheal side
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批准号:05671431
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1993
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负责人:YUMOTO Eiji
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依托单位: