Basic and clinical research for surgical treatment of unilaterallaryngeal paralysis aiming at reinnervation of the laryngeal muscle
Basic and clinical research for surgical treatment of unilaterallaryngeal paralysis aiming at reinnervation of the laryngeal muscle
批准号:
22390316
负责人:
YUMOTO Eiji
金额:
$10.57万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
喉返神经切断后立即植入神经肌蒂(NMP)瓣,有利于失神经的甲杓肌的神经再支配。此外,NMP植入在长期失神经支配的甲杓肌营养变化的恢复中是有效的。在研究期间,作者对10例患者施行了杓状软骨内收术,对32例患者施行了NMP皮瓣植入联合杓状软骨内收术。后一组患者的发音功能随时间而改善,大多数患者在喉麻痹发作前自行恢复发音。
英文摘要
The nerve-muscle pedicle (NMP) flap implantation immediately aftertransection of the recurrent laryngeal nerve facilitated reinnervation of the denervatedthyroarytenoid muscle. Further, NMP implantation was effective in the recovery fromatrophic changes in long-term denervated thyroarytenoid muscle. The authors performedarytenoid adduction in 10 patients and NMP flap implantation combined with arytenoidadduction in 32 patients during research period. The latter patient group showedtime-dependent improvement of vocal function and most of them retrieved their own voicesbefore the onset of laryngeal paralysis.
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DOI:
10.1002/lary.23241
发表时间:
2012
期刊:
Laryngoscope
影响因子:
2.6
作者:
[今泉光雅, 大森孝一, 他, Narajos N]
通讯作者:
Narajos N
披裂軟骨内転術後の咽喉頭腫脹
杓状软骨内收后咽喉肿胀
DOI:
--
发表时间:
2010
期刊:
音声言語医学
影响因子:
--
作者:
[東家 完, 湯本英二, 讃岐徹治, 熊井良彦, 西本康兵]
通讯作者:
西本康兵
Animal Model for RecurrentLaryngeal Nerve Synkinetic Reinnervationwith Immobile Vocal Fold Using SiliconTube
使用硅管固定声带进行喉返神经联动再神经支配的动物模型
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[山岸麗子, 相原一, 新家眞, 坪田一男, Kumai Y]
通讯作者:
Kumai Y
Subjective and Objective Voice Outcomes Following Arytenoid Adducation Plus Nerve-Muscle Pedicle Transfer Compared with Simple Vocal Fold
杓状腱内收加神经肌肉蒂移植后的主观和客观声音结果与简单声带的比较
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hayashi K, Ohno-Matsui K, Moriyama M, Shimada N, Hayashi W, Tokoro T, Mochizuki M, Mohammed M]
通讯作者:
Mohammed M
DOI:
10.1177/000348941011901206
发表时间:
2010-12
期刊:
Annals of Otology, Rhinology & Laryngology
影响因子:
--
作者:
[T. Aoyama;Y. Kumai;E. Yumoto;Takaaki Ito;Satoru Miyamaru]
通讯作者:
T. Aoyama;Y. Kumai;E. Yumoto;Takaaki Ito;Satoru Miyamaru
共 65 条
Synkinetic movement of the vocal fold in unilaterally paralyzed larynx
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批准号:23659798
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.25万
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财政年份:2011
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负责人:YUMOTO Eiji
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依托单位:
Basic study regarding reinnervation after recurrent laryngeal nerve paralysis
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批准号:19390435
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.32万
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财政年份:2007
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负责人:YUMOTO Eiji
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依托单位:
Effect of neurotrophic factors on regeneration of denervated recurrent laryngeal nerve
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批准号:14370547
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.42万
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财政年份:2002
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负责人:YUMOTO Eiji
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依托单位:
Experimental study for quantification of traveling mucosal wave of the vocal fold
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批准号:10671597
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1998
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负责人:YUMOTO Eiji
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依托单位:
声帯粘膜波状運動に関する実験的研究
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批准号:07671862
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:YUMOTO Eiji
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依托单位:
Vocal fold vibration viewed from tracheal side
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批准号:05671431
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1993
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负责人:YUMOTO Eiji
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依托单位:
海外基金