Study of the neural basis of vocal communications by molecular biological approaches for critical period.

我们证实，地西泮或社会隔离影响了孟加拉雀鸣叫学习的关键时期，但HVC中可塑性相关基因的表达模式没有改变。另一方面，利用cDNA微阵列技术在孟加拉雀大脑中发现了与鸣叫学习关键期相关的候选基因。我们发现语言相关基因在普通狨猴大脑的视觉、听觉和运动系统中表现出重叠的表达模式。

We confirmed that the diazepam administration or social isolation affected the critical period for song learning in Bengalese finches, but the expression patterns of plasticity-related genes in the HVC were not changed. On the other hand, candidate genes related to the critical period for song learning were found in the Bengalese finch brain by using cDNA microarray. We found the language-related genes displayed overlapping expression patterns in the ocular, auditory, and motor systems in the common marmoset brain.