The neural basis and temporal dynamics of auditory-vocal interaction

流利的语言是指发音器官在精确的时间内协调一致。本研究采用伪听觉反馈和功能磁共振成像方法，对健康成人和口吃者（PWS）的言语-声音交互作用的时间特征和神经基础进行了研究。结果表明，不同的低频分量在一个补偿基频（F_0）响应中具有主成分。这意味着基于语音-发声错误检测的语音F_0控制存在不同时序的多个神经机制。fMRI研究结果显示，右侧初级运动区、小脑、右侧额下回、壳核和小脑的激活是嗓音F_0控制的神经基础。

Fluent speech is characterized by smooth coordination of organs involved in the auditory-vocal system in precise timing. This study examined temporal characteristics and the neural basis of auditory-vocal interaction using pseudo-auditory-feedback and fMRI methods in healthy adults and people who stutter (PWS). Results showed principal components of different latencies in a compensative fundamental frequency (F_0) response. This implies multiple neural mechanisms in different timing underlying the voice F_0 control based on the auditory-vocal error detection. The result of fMRI study showed the activation of right primary motor area, cerebellum, right inferior frontal gyrus, putamen, and insula as the neural basis of the voice F_0, control.