Higher Levels of Self-Assembly of Ionic Amphiphilic Copolymers: Strategies Based on Multiple Molecular Interactions (SONS-AMPHI)

我们建议研究在水溶液和界面中由多种类型的相互作用驱动的离子/非离子两亲性大分子的层次自组装。分子结构的光谱范围将从简单的线性结构（如嵌段共聚物）到分支结构（如接枝共聚物）和更复杂的纳米颗粒（核壳和Janus型）。我们的目标是了解自组织、产生的结构和界面模式是如何由具有不同类型和范围的竞争相互作用，特别是疏水和静电相互作用的构建块的大分子结构的相互作用所控制的。我们的最终目标是创建能够以分层方式自组装的系统。本项目将在这个具有挑战性的方向探索可能的方法。参与小组的专业知识（先进的合成技术，广泛的实验表征方法以及分析和计算理论建模的结合）是很强的互补，他们的协调努力将导致对两亲性大分子系统自组织的理解达到一个新的水平。

We propose to study the hierarchical self-assembly of ionic / non-ionic amphiphilic macromolecules driven by multiple types of interactions both in aqueous solution and at interfaces. The spectrum of molecular architectures will range from simple linear structures (e.g., block copolymers) to branched structures (e.g. graft copolymers) and more complex nanoparticles (core-shell and Janus type). We aim to understand how self organization, the resulting structures and interfacial patterns are controlled by the interplay of macromolecular architecture of building blocks with different types and ranges of competing interactions, particularly hydrophobic and electrostatic interactions. Our ultimate goal is to create systems that can self-assemble in a hierarchical way. The present project will explore possible approaches in this challenging direction. The expertise of the participating groups (advanced synthetic techniques, a wide range of experimental characterization methods and the combination of analytical and computational theoretical modeling) is strongly complementary and their coordinated efforts will lead to a new level of understanding of self-organization of amphiphilic macromolecular systems.