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Analysis of the Role of Snapin in the Regulation of SNARE Complex Assembly

Analysis of the Role of Snapin in the Regulation of SNARE Complex Assembly
Snapin在SNARE复合体组装调控中的作用分析
批准号:
DP0208625
负责人:
Prof Tony Tiganis
金额:
$3.07万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2002
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2002-01-01 至 2002-12-31

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中文摘要
翻译
拟议研究的目的是研究一种蛋白质,snapin在哺乳动物细胞内不同隔间之间的膜和货物蛋白运输中所起的作用。膜运输是一个基本的细胞过程,它需要一个称为SNARES的相关分子家族。我们最近发现,snapin与SNARE家族的某些成员相互作用,这意味着在膜运输中起着关键作用。拟议的研究将为snapin和SNAREs功能的分子机制以及一般的膜运输提供重要的新见解。
英文摘要
The aims of the proposed studies are to investigate the role played by a protein, snapin in the trafficking of membranes and cargo proteins between different compartments inside mammalian cells. Membrane trafficking is a fundamental cellular process that requires a family of related molecules termed SNARES. We have recently discovered that snapin interacts with certain members of the SNARE family, implying a critical role in membrane trafficking. The proposed studies will provide important new insights into the molecular mechanisms underlying the function of both snapin and SNAREs, and membrane trafficking in general.
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Phosphatases in human disease
  • 批准号:
    nhmrc : GNT1103037
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $75.33万
  • 财政年份:
    2016
  • 负责人:
    Prof Tony Tiganis
  • 依托单位:
Phosphatases in human disease
  • 批准号:
    nhmrc : 1103037
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $51.94万
  • 财政年份:
    2016
  • 负责人:
    Prof Tony Tiganis
  • 依托单位:
Hepatic oxidative stress, PTPs & STAT signalling in obesity
  • 批准号:
    nhmrc : GNT1083837
  • 项目类别:
    Project Grants
  • 资助金额:
    $104.08万
  • 财政年份:
    2015
  • 负责人:
    Prof Tony Tiganis
  • 依托单位:
Hepatic oxidative stress, PTPs & STAT signalling in obesity
  • 批准号:
    nhmrc : 1083837
  • 项目类别:
    Project Grants
  • 资助金额:
    $72.45万
  • 财政年份:
    2015
  • 负责人:
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  • 依托单位:
海外基金