Characterisation of TCPTP as a tumour suppressor
Characterisation of TCPTP as a tumour suppressor
批准号:
nhmrc : 606605
负责人:
Prof Tony Tiganis
金额:
$39.8万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
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英文摘要
Breast cancer is the most frequent malignancy among women, with an estimated 1 million new cases per year worldwide. A family of enzymes known as protein tyrosine kinases (PTKs) are fundamental in the initiation and progression of tumour growth and they are frequently hyperactivated in breast cancer. This proposal will examine whether inactivation of the enzyme known as TCPTP contributes to PTK hyperactivation and tumorigenicity in breast cancer.
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会议论文
Phosphatases in human disease
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批准号:nhmrc : GNT1103037
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项目类别:Research Fellowships
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资助金额:$75.33万
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财政年份:2016
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负责人:Prof Tony Tiganis
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依托单位:
Phosphatases in human disease
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批准号:nhmrc : 1103037
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项目类别:Research Fellowships
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资助金额:$51.94万
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财政年份:2016
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负责人:Prof Tony Tiganis
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依托单位:
Hepatic oxidative stress, PTPs & STAT signalling in obesity
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批准号:nhmrc : GNT1083837
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项目类别:Project Grants
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资助金额:$104.08万
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财政年份:2015
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负责人:Prof Tony Tiganis
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依托单位:
Hepatic oxidative stress, PTPs & STAT signalling in obesity
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批准号:nhmrc : 1083837
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项目类别:Project Grants
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资助金额:$72.45万
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财政年份:2015
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负责人:Prof Tony Tiganis
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依托单位:
How protein tyrosine phosphatases select their substrates
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批准号:DP130103154
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项目类别:Discovery Projects
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资助金额:$23.45万
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财政年份:2013
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负责人:Prof Tony Tiganis
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依托单位:
The role of the T cell protein tyrosine phosphatase in autoimmunity
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批准号:nhmrc : 1047055
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项目类别:Project Grants
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资助金额:$43.66万
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财政年份:2013
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负责人:Prof Tony Tiganis
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依托单位:
Protein Tyrosine Phosphatases, Cellular Signaling & Human Disease
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批准号:nhmrc : 1002693
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项目类别:Research Fellowships
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资助金额:$48.52万
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财政年份:2011
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负责人:Prof Tony Tiganis
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依托单位:
Regulation of insulin signalling and glucose homeostasis by protein tyrosine phosphatases
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批准号:nhmrc : 545846
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项目类别:NHMRC Project Grants
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资助金额:$36.17万
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财政年份:2009
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负责人:Prof Tony Tiganis
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依托单位:
Tyrosine kinases and phosphatases in cell cycle checkpoint responses
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批准号:nhmrc : 436602
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项目类别:NHMRC Project Grants
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资助金额:$34.27万
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财政年份:2007
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负责人:Prof Tony Tiganis
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依托单位:
Regulation of TNF and SFK signalling in immune cells by TCPTP
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批准号:nhmrc : 384147
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项目类别:NHMRC Project Grants
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资助金额:$30.27万
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财政年份:2006
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负责人:Prof Tony Tiganis
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依托单位:
Research Fellowship - Grant ID:384149
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批准号:nhmrc : 384149
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项目类别:NHMRC Research Fellowships
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资助金额:$36.6万
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财政年份:2006
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负责人:Prof Tony Tiganis
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依托单位:
Regulation of insulin signalling & glucose homeostasis by protein tyrosine phosphatases
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批准号:nhmrc : 384146
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项目类别:NHMRC Project Grants
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资助金额:$33.59万
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财政年份:2006
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负责人:Prof Tony Tiganis
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依托单位:
Regulation and function of a novel protein tyrosine phosphatase
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批准号:DP0449749
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项目类别:Discovery Projects
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资助金额:$14.62万
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财政年份:2004
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负责人:Prof Tony Tiganis
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依托单位:
Characterisation of a novel protein tyrosine phosphatase
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批准号:DP0345146
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项目类别:Discovery Projects
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资助金额:$4.1万
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财政年份:2003
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负责人:Prof Tony Tiganis
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依托单位:
Protein tyrosine phosphatases in the regulation of insulin receptor signalling and glucose uptake
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批准号:nhmrc : 236869
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项目类别:NHMRC Project Grants
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资助金额:$28.36万
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财政年份:2003
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负责人:Prof Tony Tiganis
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依托单位:
Regulation and function of the protein tyrosine phosphatase TCPTP in mitosis
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批准号:nhmrc : 236870
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项目类别:NHMRC Project Grants
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资助金额:$30.36万
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财政年份:2003
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负责人:Prof Tony Tiganis
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依托单位:
Analysis of the Role of Snapin in the Regulation of SNARE Complex Assembly
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批准号:DP0208625
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项目类别:Discovery Projects
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资助金额:$3.07万
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财政年份:2002
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负责人:Prof Tony Tiganis
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依托单位:
Function and regulation of the protein tyrosine phosphatase TCPTP
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批准号:nhmrc : 7757
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项目类别:Career Development Fellowships
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资助金额:$19.36万
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财政年份:2000
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负责人:Prof Tony Tiganis
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依托单位:
Protein Tyrosine Phosphatases in Cell Proliferation, Migration and Angiogenesis
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批准号:nhmrc : 990891
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项目类别:NHMRC Project Grants
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资助金额:$24.69万
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财政年份:1999
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负责人:Prof Tony Tiganis
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依托单位:
海外基金