Nebraska Center for Nanomedicine

摘要 多学科内布拉斯加州纳米医学中心(NCN)，成立于2008年，与 生物医学卓越研究(COBRE)资助，正在建设一个国家和国际公认的 纳米医学卓越计划，结合了材料、制药和 由创新研究驱动的生物科学。NCN已经完成了最初的目标并增强了 内布拉斯加州的生物医学研究能力，通过创建具有战略联系的强大研究基础设施 项目，并通过指导一批有才华的初级教员取得独立成功。年的前9年 基金，由NCN资助的初级教员获得了超过1800万美元的新研究资金，8个NCN 受训人员已获得终身教职和/或晋升，8名新的初级和高级教员具有与以下方面相关的专业知识 NCN被招募到药学院。我们的毕业生已被任命为编辑委员会成员，为 在审查小组上，并收到了无数次邀请来主持研讨会。这份NCN Cobre延续提案 详细说明了我们计划保持一个具有全国知名度和国际知名度的生物医学研究中心。 推动NCN朝着这些目标迈进的具体目标是：1)继续扩大现有研究 通过协作跨学科研究的支持和初级教员的指导来发挥优势；2) 加强对隶属于NCN的调查人员的研究能力、创新和资金支持；3) 确保科学核心设施的可持续性，这些设施对中心的持续发展和 为广大研究社区服务。这些目标的实现将使NCN走出阶段 III提供资金，作为纳米医学卓越研究的自给自足中心，能力有所增强 通过个人和多名研究人员、项目范围的研究拨款寻求项目支持。 通过开发和临床翻译有效的纳米药物来诊断和治疗糖尿病 在人类疾病方面，NCN最终将为内布拉斯加人和社会的健康带来重大好处 逍遥法外。

ABSTRACT The multidisciplinary Nebraska Center for Nanomedicine (NCN), established in 2008 with the Center for Biomedical Research Excellence (COBRE) funding, is building a nationally and internationally recognized program of excellence in nanomedicine that combines broad expertise in material, pharmaceutical and biological sciences driven by innovative research. NCN has completed its original objectives and enhanced Nebraska's biomedical research capacity by creating a strategically linked infrastructure of strong research programs and by mentoring a cadre of talented junior faculty to independent success. In the first 9 years of funding, the NCN-funded junior faculty members obtained over $18 million in new research funds, eight NCN trainees have been tenured and/or promoted, eight new junior and senior faculty with expertise relevant to NCN were recruited to the College of Pharmacy. Our graduates have been appointed to editorial boards, serve on review panels, and have countless invitations to present seminars. This NCN COBRE continuation proposal details our plan to maintain a biomedical research center of national prominence and international recognition. The specific aims that move the NCN toward these goals are: 1) continue to expand existing research strengths through the support of collaborative interdisciplinary research and mentorship of junior faculty; 2) strengthen research capabilities, innovation and funding support for investigators affiliated with the NCN; 3) assure sustainability of scientific core facilities that are essential for the continued growth of the Center and serve the research community at large. The realization of these aims will allow the NCN to emerge from Phase III funding as self-sustaining center of research excellence in nanomedicine, with an increased capacity to pursue programmatic support through individual and multi-investigator, program-wide research grants. Through the development and clinical translation of effective nanomedicines for diagnosis and therapy for human diseases, the NCN will ultimately provide significant benefits for the health of Nebraskans and society at large.