South Carolina Clinical and Translational Research Institute (SCTR)

项目摘要-SCTR协会家长奖UL1-TR001450 自2009年以来，南卡罗来纳州临床和翻译研究所(SCTR)转变了 整个南卡罗来纳州(SC)的研究环境，通过创建支持高 高质量的临床和转化性研究(CTR)，并促进协作和创新。总部设在 南卡罗来纳医科大学(MUSC)与利益攸关方接触并在全州范围内创建了 伙伴关系，以改善护理和解决整个SC健康的社会决定因素。然而，超过75%的 南卡罗来纳州的10%是农村地区，所有46个县都有被指定为医疗服务不足的地区，因此健康差距 仍然是一个问题。在接下来的五年里，SCTR将加强对这些医疗服务不足的人的接触 与克莱姆森大学健康推广计划和南加州大学远程健康中心合作的领域 卓越中心。以实施和传播以及发现为重点，我们将制定 并展示创新技术和外联活动，以改善我们利益相关者的健康。我们将建造 总结以往的成功经验，并采用创新办法，通过以下目标在整个SC范围内扩大CTR： 目标1.为所有各级推广和加强高质量、创新、灵活的课程和培训经验 CTR劳动力，特别强调加强劳动力异质性和团队科学。 目标2.让不同的利益攸关方群体作为CTR的积极合作伙伴参与，以解决卫生保健优先事项，同时 加强关于协作和参与的科学知识基础。 目标3.通过吸引调查人员，促进研究的全翻译范围内更大程度的包容性 来自许多学科和来自不同人口背景和地理区域的患者群体。 目标4.制定、示范和传播创新方法和程序，以解决障碍和 加速将研究发现转化为改善人类健康的成果，可概括为 多种多样的练习环境。 目标5.通过开发安全和创新的方法加强翻译研究的开展 影响CTR方方面面的信息学和数字健康解决方案、工具和方法。 SCTR的愿景是成为促进创新科学转化为实践的主要力量，以解决 南卡罗来纳州及其他地区公民的健康优先事项。为了实现这一愿景，SCTR的使命是催化 开发方法和技术，将生物医学发现更有效地转化为 改善个人和公共健康的干预措施。SCTR将作为全州范围的学术之家 CTR与SC的医疗保健系统完美集成，为创新、 高效、多学科的研究和研究培训。我们将在SCTR内部与我们的合作伙伴一起工作 SC和与CTSA联盟的合作以实现这一愿景。

PROJECT SUMMARY – SCTR INSTITUTE Parent Award UL1-TR001450 Since 2009, the South Carolina Clinical and Translational Research Institute (SCTR) has transformed the research environment across South Carolina (SC) by creating a Learning Health System that supports high- quality clinical and translational research (CTR) and fosters collaboration and innovation. Headquartered at the Medical University of South Carolina (MUSC), SCTR has engaged stakeholders and created statewide partnerships to improve care and address social determinants of health across SC. However, greater than 75% of SC is rural, and all 46 counties contain areas designated as medically underserved, so health disparities remain an issue. Over the next five years, SCTR will strengthen its outreach to these medically underserved areas through collaboration with the Clemson University Health Extension Program and the MUSC Telehealth Center of Excellence. With a focus on implementation and dissemination as well as discovery, we will develop and demonstrate innovative technologies and outreach to improve the health of our stakeholders. We will build on prior successes and introduce innovative approaches to expand CTR across SC through the following aims: Aim 1. Extend and enhance high-quality, innovative, flexible curricula and training experiences for all levels of the CTR workforce, with particular emphasis on enhancing workforce heterogeneity and team science. Aim 2. Engage a diverse group of stakeholders as active partners in CTR to address health care priorities while enhancing the scientific knowledge base about collaboration and engagement. Aim 3. Promote greater inclusion across the full translational spectrum of research by engaging investigators from many disciplines and patient populations from diverse demographic backgrounds and geographic areas. Aim 4. Develop, demonstrate and disseminate innovative methods and processes to address barriers and accelerate the translation of research discoveries to improvements in human health that can be generalized to a variety of practice settings. Aim 5. Enhance the conduct of translational research through the development of secure and innovative informatics and digital health solutions, tools and methodologies that affect every aspect of CTR. SCTR’s vision is to be a major force in facilitating the translation of innovative science into practice to address the health priorities of the citizens of SC and beyond. To achieve this vision, SCTR’s mission is to catalyze the development of methods and technologies that lead to more efficient translation of biomedical discoveries into interventions that improve individual and public health. SCTR will serve as the statewide academic home for CTR, one that is well-integrated with SC’s healthcare systems and provides essential support for innovative, efficient, multidisciplinary research and research training. We will work within SCTR, with our partners across SC and with the CTSA Consortium to realize this vision.