Administrative Core

抽象--管理核心 杜克大学自闭症卓越中心的总体目标是描述自闭症的共病症状 注意缺陷多动障碍(ADHD)影响早期发现、临床表现、神经功能障碍 自闭症谱系儿童的特征、发展轨迹和治疗结果 精神障碍(ASD)。行政(“行政”)核心将作为中心的枢纽，协调和 监督所有研究项目和核心，以使它们作为一个整体在 融合、协同的时尚。管理核心的目标是促进沟通和 团队调查人员之间的协作，减轻中心调查人员、监控人员的行政负担 法规遵从性，并确保科学严谨、进步和生产力。管理核心将是 负责实现以下具体目标：(1)协调、促进和简化沟通 在中心的所有组成部分之间，确保在所有阶段的密切合作和科学进步 研究项目。为了实现这一目标，行政核心将每月协调执行委员会 以及全中心会议，项目和核心领导以及其他关键人员和工作人员将在会上 审查目标招聘目标、支出汇总、资源、时间表和可交付成果；确定 实现中心目标的障碍；并制定和实施应对障碍的战略；(2) 提供对中心的全面管理和监督。核心将监督和支持中心的 通过设定目标、定义交付成果以及密切监控和评估进展和 生产力，从而确保朝着里程碑和交付成果及时取得进展。对每个项目进行评估 核心，以及整个中心，将基于相对于这些商定的科学进步 以及(3)提供及时的财务会计，并确保 遵守所有机构、州和联邦研究和道德准则。核心将提供 专业知识和基础设施，以确保财务管理和遵守相关大学、州、 DHHS、NIH和联邦研究法规，包括与人类受试者研究相关的法规。《管理员》 CORE将与所有项目和核心紧密相连，并将其整合在一起。通过这种方式，管理核心将 确保统一、合规的研究工作，并将支持中心的总体目标，以阐明早期 伴发ADHD症状的检测、发育轨迹、神经特征和治疗 患有自闭症的儿童。

ABSTRACT – Administrative Core The overall goal of the Duke Autism Center of Excellence is to characterize how co-occurring symptoms of attention deficit hyperactivity disorder (ADHD) influence the early detection, clinical presentation, neural signatures, developmental trajectories, and treatment outcomes of young children with autism spectrum disorder (ASD). The Administrative (“Admin”) Core will serve as the hub for the Center, coordinating and overseeing all research projects and cores so that they function effectively and efficiently as a whole in an integrated and synergistic fashion. The goals of the Admin Core are to promote communication and collaboration among team investigators, reduce the administrative burden on Center investigators, monitor regulatory compliance, and ensure scientific rigor, progress, and productivity. The Admin Core will be responsible for achieving the following specific aims: (1) coordinate, promote, and streamline communication across all components of the Center to ensure close collaboration and scientific progress through all phases of the research program. To accomplish this aim, the Admin Core will coordinate monthly Executive Committee and Center-wide meetings at which project and core Leads and other key personnel and staff members will review target recruitment goals, expenditure summaries, resources, timelines, and deliverables; identify any barriers to achieving the Center's goals; and develop and implement strategies for addressing barriers; (2) provide overall management and oversight of the Center. The Core will oversee and support the Center's scientific efforts by setting goals, defining deliverables, and closely monitoring and evaluating progress and productivity, thereby ensuring timely progress toward milestones and deliverables. Evaluation of each project and core, as well as the overall Center, will be based on scientific progress relative to these agreed-upon milestones and in relation to expected expenditures; and (3) provide timely financial accounting and ensure compliance with all institutional, state, and federal research and ethical guidelines. The Core will provide expertise and infrastructure to ensure financial management and compliance with relevant university, state, DHHS, NIH, and federal research regulations, including those related to human subjects research. The Admin Core will be closely connected to and will integrate all projects and cores. In this way, the Admin Core will ensure a unified, compliant research effort and will support the Center's overall goals to shed light on the early detection, developmental trajectories, neural signatures, and treatment of co-occurring ADHD symptoms in young children with ASD.