Southeast Collaborative Alliance for Stroke Trials (SE-CoAST)

中风的负担继续不成比例地影响美国东南部-所谓的 中风带。为这些人群提供中风教育、预防、急性治疗、康复和治疗， 特别是参与临床研究，仍然是一个挑战。开发一种功能强大的临床和 研究多中心的基础设施，使这些人群在高风险的中风是至关重要的，以改变 不成比例的中风负担。 中风护理和研究，从预防，到急性治疗，最后到康复。 最好在多学科医疗保健团队的背景下提供和执行。中风 医疗保健系统整合了地理区域内的医疗保健资源，被认为是最佳的 实践，确保区域内的最佳护理。研究也是最好的工作范围内现有的 临床中风护理系统，利用对齐领域-患者教育，参与，中风 医疗保健界的认识，以及所有人对研究参与机会的认识 医疗保健设置。 在这项申请中，扩大的东南中风试验合作联盟（SE-CoAST）及其 调查人员仍然致力于担任StrokeNet的区域协调中心。SE-Coast现在 4个三级护理学术医疗中心之间的扩大，强大的合作，位于心脏 中风带：沿着南卡罗来纳州海岸的南卡罗来纳州医科大学，东部的奥古斯塔大学， 佐治亚州、南卡罗来纳州北部的格林维尔健康系统和棕榈健康/南卡罗来纳州大学 南卡罗来纳州中部地区的卫生系统。这个扩大的网络的最大优势是我们现有的 研究和中风护理提供的伙伴关系。SE-CoAST现在几乎服务于SC的整个州， 大部分GA，鉴于我们的集水区的广度以及我们的显着遥距存在 在东南部。SE-CoAST的总体目标仍然是：1）利用SE-CoAST组织， 增加我们各州参与急性、预防和恢复StrokeNet试验的居民人数; 2)继续我们在全国范围内StrokeNet活动中的领导作用; 3）利用SE-CoAST临床前 研究人员在开发有前途的治疗干预措施，在中风网络的研究; 4）继续， 支持和提高我们的StrokeNet学者的职业发展。

The burden of stroke continues to disproportionately impact the Southeast United States – the so-called Stroke Belt. Reaching these populations for stroke education, prevention, acute treatment, rehabilitation, and in particular participation in clinical research, remains a challenge. Developing a highly functional clinical and research multicenter infrastructure to engage these populations at high risk for stroke is critical to change the disproportionate stroke burden. Stroke care and research, from prevention, through acute treatment, and finally through recovery / rehabilitation, are best provided and performed in the context of multidisciplinary healthcare teams. Stroke Systems of Care, integrating healthcare resources across a geographic region, are recognized as best practice, ensuring optimal care within the region. Research is also best performed working within the existing clinical stroke systems of care, capitalizing on areas of alignment – patient education, engagement, stroke awareness in the healthcare community, and awareness of research participation opportunities in all healthcare settings. In this application, the expanded Southeast Collaborative Alliance for Stroke Trials (SE-CoAST) and its investigators remain committed to serving as a Regional Coordinating Center in StrokeNet. SE-CoAST is now an expanded, robust collaboration between 4 tertiary care academic medical centers situated in the heart of the Stroke Belt: the Medical University of South Carolina along the SC coast, the Augusta University in eastern GA, the Greenville Heath System in the upstate of SC, and the Palmetto Health / University of South Carolina Health System in the midlands of SC. The greatest strength of this expanded network is our existing partnerships in research and stroke care delivery. SE-CoAST now serves nearly the entire state of SC and a large proportion of GA, given the breadth of our catchment areas as well as our significant telestroke presence across the Southeast. The overall goals of SE-CoAST remain: 1) to leverage the SE-CoAST organization to increase the number of residents of our states participating in acute, prevention and recovery StrokeNet trials; 2) to continue our leadership roles in StrokeNet activities nationally; 3) to utilize SE-CoAST preclinical researchers in developing promising therapeutic interventions for study within StrokeNet; 4) to continue to support and enhance the career development of our StrokeNet scholars.