Shared Resource: Prevention Center

项目概要：预防中心共享资源（PCSR） 预防中心共享资源（PCSR）的目标是促进跨学科，协作 联盟内的研究，重点是更好地理解行为/生活方式的贡献 修饰、营养、身体活动和肥胖对癌症发展、预后和存活率的影响。 PCSR位于Fred Hutch（FH）中心，通过向财团调查员提供 获得训练有素的工作人员和全方位服务的研究设施（超过10，000 nsf），其中包括一个研究诊所 (RC)运动研究中心（ERC）和人类营养实验室（HNL）。驻地协调员配备了医务人员， 能够进行临床评估、收集生物标本（包括各种活检）并获得 详细的人体测量ERC进行运动训练和测试，包括最大摄氧量、肺活量测定和 间接量热法训练有素的运动生理学家可以帮助研究人员设计量身定制的运动 计划和监督研究参与者的锻炼课程。HNL提供全面的支持 进行人类喂养研究以及行为和社区营养的食物组成部分 干预研究。服务包括研究饮食设计、食品生产和交付、膳食服务、数据 收集，以及根据饮食摄入方案对研究参与者进行管理和监测。PCSR 还为技术人员提供培训和认证，并作为支持资源和培训设施 为研究人员，博士后和临床研究员，以及对运动科学和营养感兴趣的学生 research. 鉴于美国受癌症影响的人数越来越多，识别出 可预防的癌症原因以及改善癌症幸存者生活质量的方法。的 PCSR的长期目标是保持自身作为联盟独特的尖端资源， 促进我们对行为/生活方式、营养、身体活动和肥胖相关知识的进步 癌症发展、预后和存活率的贡献者。

PROJECT SUMMARY: PREVENTION CENTER SHARED RESOURCE (PCSR) The goal of the Prevention Center Shared Resource (PCSR) is to facilitate transdisciplinary, collaborative research within the Consortium, focused on better understanding the contributions of behavior/lifestyle modification, nutrition, physical activity, and obesity to cancer development, prognosis, and survivorship. Centrally located at Fred Hutch (FH), the PCSR accomplishes this by providing Consortium investigators access to well-trained staff and a full-service research facility (over 10,000 nsf) that contains a Research Clinic (RC), Exercise Research Center (ERC), and Human Nutrition Lab (HNL). The RC is staffed with medical personnel who can perform clinical assessments, collect biospecimens (including various biopsies), and obtain detailed anthropometry. The ERC conducts exercise training and testing, including VO2 max, spirometry, and indirect calorimetry. Trained exercise physiologists are available to help investigators design tailored exercise programs and to oversee exercise sessions for study participants. The HNL provides comprehensive support for the conduct of human feeding studies as well as the food component of behavioral and community nutrition intervention studies. Services include study diet design, food production and delivery, meal service, data collection, and study participant management and monitoring according to diet intake protocols. The PCSR also provides training and certification for technical staff and serves as a support resource and training facility for investigators, post-doctoral and clinical fellows, and students interested in exercise science and nutrition research. Given the increasing number of individuals in the US affected by cancer, it is of great importance to identify causes of cancer that are preventable and ways to improve the quality of life among cancer survivors. The long-term goal of the PCSR is to maintain itself as a unique, cutting-edge resource for the Consortium, to facilitate advances in our knowledge of the behavioral/lifestyle, nutritional, physical activity, and obesity-related contributors to cancer development, prognosis, and survivorship.