Technology-based intervention for alcohol-related sexual risk behaviors in young women with sexual victimization histories

这个独立之路奖的长期目标有两个方面：（1）支持候选人Blayney博士 在建立一个独立的研究计划和（2）促进她从博士后研究员过渡到 独立研究员。到目前为止，Blayney博士的研究主要集中在 青年人遭受性侵害的后果，包括与 性侵害风险作为博士后培训的一部分，布莱尼博士的工作已经开始研究 酒精对有和没有性侵害的年轻女性性风险模式的近端影响 历史Blayney博士寻求将她的培训从基本的酒精研究扩展到开发和测试简介， 以技术为基础的干预措施，以减少酒精和性风险。这一长远目标将得以实现 通过五年培训计划，包括精心挑选的导师团队以及有针对性的课程， (e.g.,课程、研讨会、讲习班）和实践培训经验。拟议研究的目标是 开发和测试一种专门的基于网络的干预措施，以减少与酒精有关的危险性行为。 在有性受害史的年轻妇女中，这是一个高风险和服务不足的群体。期间 指导阶段（K99），干预措施将以用户为中心的设计（目标1），创新 技术部门采取的将目标人群纳入发展各个阶段的方法。在 目标1a，将起草干预内容并向目标人群介绍（即，年轻女性 性受害历史）以获得用户反馈。在目标1b中，将使用快速评估方法评估干预设计。 在对干预进行编程之前，对用户反馈进行原型设计。一旦编程，目标1c将涉及 对目标人群进行干预交付的可用性测试。在制定干预措施之后，目标2 将通过网络公开试验评估干预的可行性和可接受性。在独立阶段 (R00)，将进行一项基于网络的随机对照试验，以测试干预效果（目标3a）、变化机制（目标 3b），和潜在的主持人（目标3c）。调查结果将作为NIAAA R 01提交的试验数据， R 00阶段。这一应用的培训计划将侧重于干预措施的开发和测试， 创新方法，以加强基于技术的干预发展，以及先进的统计。导师 (Drs.乔治，贝达-吉利根，线索戴维斯，Rhew）和顾问（比林斯博士，威德曼）致力于 候选人的培训，每个人都将提供独特的专业知识的研究和培训计划。支持从这 奖项将是至关重要的候选人的发展，作为一个独立的科学家谁可以贡献， 通过开发和测试基于技术的干预措施来减少酒精和性风险。 华盛顿大学非常适合提供一流的培训经验，并将促进NIH的 使命是培养早期研究人员，他们可以在长期研究资金方面具有竞争力。

The long-term objective of this Pathway to Independence Award is two-fold: (1) support candidate Dr. Blayney in building an independent research program and (2) facilitate her transition from postdoctoral fellow to independent faculty researcher. To date, Dr. Blayney's research has focused on the risks for and consequences of sexual victimization in young adults, including the social and sexual contexts associated with sexual victimization risk. As part of postdoctoral training, Dr. Blayney's work has begun to examine the proximal influence of alcohol in sexual risk patterns for young women with and without sexual victimization histories. Dr. Blayney seeks to expand her training from basic alcohol research to developing and testing brief, technology-based interventions to reduce alcohol and sexual risk. This long-term objective will be achieved through a five-year training plan involving a carefully selected mentor team as well as targeted coursework (e.g., classes, seminars, workshops) and hands-on training experiences. The goal of the proposed research is to develop and test a specialized web-based intervention to reduce alcohol-related sexual risk behaviors among young women with sexual victimization histories, a high-risk and underserved group. During the mentored phase (K99), the intervention will be developed with user centered design (Aim 1), an innovative approach from the technology sector that incorporates the target population into all stages of development. In Aim 1a, intervention content will be drafted and presented to the target population (i.e., young women with sexual victimization histories) for user feedback. In Aim 1b, intervention design will be evaluated using rapid prototyping for user feedback before the intervention is programed. Once programed, Aim 1c will involve usability testing of intervention delivery with the target population. Following intervention development, Aim 2 will assess intervention feasibility and acceptability with a web-based open trial. During the independent phase (R00), a web-based RCT will be conducted to test intervention efficacy (Aim 3a), mechanisms of change (Aim 3b), and potential moderators (Aim 3c). Findings will serve as pilot data for an NIAAA R01 submission during the R00 phase. The training plan for this application will focus on intervention development and testing, innovative methods to enhance technology-based intervention development, and advanced statistics. Mentors (Drs. George, Bedard-Gilligan, Cue Davis, Rhew) and consultants (Drs. Billings, Widman) are committed to the candidate's training and each will provide unique expertise to the research and training plan. Support from this award will be essential to the candidate's development as an independent scientist who can contribute to alcohol research by developing and testing technology-based interventions to reduce alcohol and sexual risk. The University of Washington is well suited to provide a stellar training experience and will promote NIH's mission to develop early investigators who can be competitive for long-term research funding.