Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network

 描述(由申请人提供)：新生儿重症监护病房多中心网络(NRN)由NICHD于1986年建立，目的是在高度优先的领域快速设计、进行和发布临床试验。我们是自1986年以来在每一轮比赛中都取得成功的仅有的两个中锋之一。我们对继续参加北大西洋公约组织的前景感到兴奋。我们将证明我们将继续毫无疑问地满足被纳入为中心的所有要求。我们的人员在他们的专业知识和生产力方面是无与伦比的，这从我们在所有试验和后续行动中一贯的高注册率中可见一斑。 超过90%的税率。我们的注册人数一直位居全国前列，因为我们的专职人员全天候招聘，包括夜间、周末和节假日。此外，我们的医疗和护理人员都毫不含糊地相信，通过研究可以改善患者护理，鼓励家属参与，并致力于严格遵守协议。我们庞大多样的先天分娩服务基本上没有回传损失，是新生儿临床试验的理想选择。我们有完整的儿科小组专家(包括积极参与儿科外科、眼科和心脏病学的合作研究人员)来进行试验。此外，CWRU在儿科药理学、肺病学、生物医学工程、呼吸治疗以及CWRU CTSA的蛋白质组学和基因组学核心方面带来了专门的专业知识，这些都丰富了NRN。我们不仅表现出了与其他中心合作的非凡能力，而且还承担了许多领导角色。我们已经为长期的后续行动设定了标准。全国乃至世界各地的中心都实施了CWRU方法，以出色的保留率跟踪早产儿进入成年期。CWRU通过指导新中心，使他们能够快速实施IRB提交、注册和遵守协议，在每个周期过渡期间持续提高NRN的生产力。我们拥有来自CWRU医学院、大学医院病例医学中心、儿科和生殖生物学系以及新生儿和母胎医学部的最坚定的机构支持和空间和资源承诺。我们热切期待NRN的下一个周期，并将继续引领和创新。

 DESCRIPTION (provided by applicant): The Multicenter Network of Neonatal Intensive Care Units (NRN) was established by the NICHD in 1986 to rapidly design, conduct and publishes clinical trials in high priority areas. We are one of only two centers that have successfully competed in every round since 1986. We are excited by the prospect of continuing our participation in the NRN. We will demonstrate that we continue to unquestionably meet all the requirements for inclusion as a center. Our personnel are unparalleled in their expertise and productivity as evidenced by our consistently high enrollment rates in all trials and our follow-up rates which exceed 90%. Our enrollments are consistently among the highest in the NRN because our dedicated personnel recruit 24/7 including nights, weekends and holidays. In addition, both our medical and nursing staffs believe unequivocally that patient care is improved through research, encourage families to participate, and are committed to meticulous adherence to protocols. Our large diverse inborn delivery service with essentially no loss to back transport is ideal for neonatal clinical trials. We have a full complement of pediatric subspecialists (including actively engaged co-investigators in Pediatric Surgery, Ophthalmology and Cardiology) available to conduct trials. In addition, CWRU brings special expertise in Pediatric Pharmacology, Pulmonology, Biomedical Engineering, Respiratory Therapy, and the Proteomics and Genomics Cores at the CWRU CTSA that all enrich the NRN. We have not only shown exceptional ability to collaborate with other centers, but we have assumed many leadership roles. We have set the bar for long term follow-up. Centers across the country, and indeed across the world, have implemented CWRU methods to track former preterm infants into adulthood with excellent retention. CWRU has consistently enhanced the productivity of the NRN at every cycle transition by mentoring new centers to enable them to rapidly implement IRB submissions, enrollment, and adherence to protocols. We have the firmest institutional backing with commitments of space and resources from the CWRU School of Medicine, University Hospitals Case Medical Center, the Departments of Pediatrics and Reproductive Biology and the Divisions of Neonatology and Maternal Fetal Medicine. We eagerly anticipate the next cycle of the NRN and will continue to lead and innovate.