Center for Neural Circuits in Addiction

项目总结/摘要 本行政补充建议检查利益相关者对脑深部电刺激（DBS）的看法， 治疗难治性成瘾的潜在疗法这一建议扩展了神经科学的工作， 由NIDA成瘾神经回路中心（1 P30 DA 048742 - 01 A1）进行，以解决一个关键的近- 术语翻译障碍：是否像DBS这样的神经技术疗法，这是该中心小说的一部分， 以电路为导向的翻译工作，提高了关键利益相关者的社会和道德问题。金资助的工作 本增刊将为中心和成瘾研究领域建立一个关键的伦理学证据基础。 这项研究将侧重于两个目标。首先是对成瘾的参与者进行定性访谈 关于DBS的治疗和恢复。这项研究将捕捉参与者的成瘾经历，并探索 DBS作为未来成瘾治疗的伦理维度。第二个目标是收集定性和定量的数据， 以及成瘾者感知社会支持的定量数据。NIDA成瘾神经回路中心 旨在对成瘾和成瘾治疗产生现实影响，包括开发新的治疗方法。 比如DBS该项目将进行生物伦理学研究，以帮助为深入的 大脑刺激在成瘾领域，并将通过生物伦理学的参与发展生物伦理学能力， 接受定性面试的实习生。

PROJECT SUMMARY/ABSTRACT This administrative supplement proposes to examine stakeholder views on deep brain stimulation (DBS) as a potential therapy for treatment-resistant addiction. This proposal extends the neuroscience work being conducted by the NIDA Center for Neural Circuits in Addiction (1P30DA048742-01A1) to address a critical near- term translational barrier: whether neurotechnology therapies like DBS, which are part of the Center's novel, circuit-oriented translational efforts, raise social and ethical concerns among key stakeholders. Work funded by this supplement will develop a critical ethics evidence base for the Center and the field of addiction research. This study will focus on two aims. The first is to conduct qualitative interviews with participants in addiction treatment and recovery about DBS. The study will capture participant's experiences with addiction and explore the ethical dimensions of DBS as a future treatment for addiction. The second aim is to collect both qualitative and quantitative data on perceived social support in addiction. The NIDA Center for Neural Circuits in Addiction aims to have a real-world impact on addiction and addiction treatment, including developing novel treatment interventions, like DBS. This project will both conduct bioethics research to help inform the development of deep brain stimulation in the area of addiction and will develop bioethics capacity through involvement of a bioethics trainee in qualitative interviewing.