Establishment of the Bat Resource Center for the Study of Zoonotic Diseases

项目摘要 该提案概述了建立蝙蝠资源中心用于人畜共患病研究的要求 科罗拉多州立大学。BAT资源中心是一家耗资799万美元的设施，位于该中心附近 媒介传播疾病和落基山地区生物遏制实验室。它是唯一的 被设计成一个具有成功繁殖所需的环境和生物安全控制的隔膜 并饲养蝙蝠作为动物模型。这个重要的动物模型对于我们理解 病毒的致病机制和疾病传播，因为蝙蝠已经被证明是许多 人类病原体，包括最近的新冠肺炎大流行。蝙蝠资源中心将极大地 增强我们研究这些代理人的能力，并将作为其他使用BAT的国家资源 模特们。

Project Summary This proposal outlines request to establish the Bat Resource Center for the Study of Zoonotic Diseases at Colorado State University. The Bat Resource Center is a $7.99M facility located adjacent to the Center for Vectorborne Disease and the Rocky Mountain Regional Biocontainment Laboratory. It is uniquely designed to be a vivarium with the necessary environmental and biosafety controls to successfully breed and maintain bats for use as animal models. This important animal model is critical to our understanding of viral pathogenesis and disease transmission as bats have been shown to be a reservoir for a number of human pathogens including the recent COVID-19 pandemic. The Bat Resource Center will greatly enhance our abilities to study these agents and will serve as a national resource for others using bat models.