Expanding xenosurveillance capabilities in central America
扩大中美洲的异种监视能力
基本信息
- 批准号:10189517
- 负责人:
- 金额:$ 18.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-06-11 至 2023-05-31
- 项目状态:已结题
- 来源:
- 关键词:AcheAffectAfricaAmericasAngerAnimalsBiteBloodBlood capillariesBlood specimenCentral AmericaChildClinical DataClinical MedicineCommunicable DiseasesCommunitiesCulicidaeDataDetectionDevicesDiseaseDomestic AnimalsEbola virusEmerging Communicable DiseasesEnrollmentEntomologyEnvironmentEpidemicExanthemaFeverFrequenciesGuatemalaHateHealthHomeHourHouseholdHumanLaboratoriesLaboratory StudyLatin AmericaMethodologyMethodsMiddle EastMiddle East Respiratory Syndrome CoronavirusMidgutMindMonitorNeedlesPainPaperPathogen detectionPerformancePilot ProjectsPopulationProcessPublic HealthQuantitative Reverse Transcriptase PCRRNAReportingResourcesRuralSamplingSiteSpottingsSymptomsSyndromeSystemTemperatureTimeValidationVenipuncturesVenous blood samplingVeterinariansVeterinary MedicineViralVisiting NurseWorkYellow fever virusZoonosesbaseburden of illnesscohortdesigndetection limitemerging pathogenfield studyhealth economicsinnovationinsightmemberminimally invasivemultidisciplinarynext generation sequencingpandemic diseasepathogenpoor communitiesprospectivesurveillance datasyndromic surveillancetooltransmission processvirology
项目摘要
This proposal is for an R21, Expanding xenosurveillance capabilities in Central America. The project is a highly
multidisciplinary effort that includes collaborators with expertise in virology, public health entomology,
surveillance, and human clinical and veterinary medicine. Our study is based on the idea that mosquitoes can
serve as surveillance tools because they are essentially autonomous blood sampling devices. Freshly fed
mosquitoes are collected from within dwellings and blood is used for surveillance purposes. If successful, our
work would have the impact of simplifying certain types of surveillance that require human blood because
although most people hate it when they and their children are stuck with needles, they don’t seem to mind
mosquitoes being removed from within their homes. In addition, our approach has the potential to make
sampling from animals safer by vastly reducing the need for direct contact with fearful and angry animals that
bite, kick, etc..
Aim 1 focuses on validating xenosurveillance through a direct comparison to human-based syndromic
surveillance. Aim 2 is designed to maintain the scientific rigor of our work by obtaining quantitative estimates of
the sensitivity of Cx. quinquefasciatus and Ae. aegypti for xenosurveillance.
This proposal leverages significant prior work on xenosurveillance that has focused on An. gambiae in W.
Africa, and an ongoing pilot study of xenosurveillance in rural Guatemala.
该提案是关于R21的,旨在扩大中美洲的异种监视能力。这个项目是一个高度
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Gregory David Ebel其他文献
Gregory David Ebel的其他文献
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{{ truncateString('Gregory David Ebel', 18)}}的其他基金
Arbovirus population biology: temperature impacts on selection and collective dynamics
虫媒病毒种群生物学:温度对选择和集体动态的影响
- 批准号:
10568405 - 财政年份:2023
- 资助金额:
$ 18.55万 - 项目类别:
Establishment of the Bat Resource Center for the Study of Zoonotic Diseases
建立人畜共患疾病研究蝙蝠资源中心
- 批准号:
10374306 - 财政年份:2021
- 资助金额:
$ 18.55万 - 项目类别:
Expanding xenosurveillance capabilities in central America
扩大中美洲的异种监视能力
- 批准号:
10041581 - 财政年份:2020
- 资助金额:
$ 18.55万 - 项目类别:
Emergence of tick borne encephalitis in North America
北美出现蜱传脑炎
- 批准号:
10312001 - 财政年份:2018
- 资助金额:
$ 18.55万 - 项目类别:
Emergence of tick borne encephalitis in North America
北美出现蜱传脑炎
- 批准号:
10680171 - 财政年份:2018
- 资助金额:
$ 18.55万 - 项目类别:
Emergence of tick borne encephalitis in North America
北美出现蜱传脑炎
- 批准号:
10526290 - 财政年份:2018
- 资助金额:
$ 18.55万 - 项目类别:
Emergence of tick borne encephalitis in North America
北美出现蜱传脑炎
- 批准号:
10063475 - 财政年份:2018
- 资助金额:
$ 18.55万 - 项目类别:
Role of cell tropism for Zika virus transmission and pathogenesis
细胞向性在寨卡病毒传播和发病机制中的作用
- 批准号:
9268283 - 财政年份:2017
- 资助金额:
$ 18.55万 - 项目类别:
Predicting genetic determinants of Zika virus emergence
预测寨卡病毒出现的遗传决定因素
- 批准号:
9284379 - 财政年份:2016
- 资助金额:
$ 18.55万 - 项目类别:
Quasispecies dynamics in arborvirus persistence, emergence and fitness
虫媒病毒持久性、出现和适应性的准种动态
- 批准号:
7418914 - 财政年份:2007
- 资助金额:
$ 18.55万 - 项目类别:
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