Resonance and aeroacoustic relationship in velopharyngeal insufficiency

项目摘要 这项K25导师量化研究职业发展奖的目标是使候选人能够 在一项研究计划的背景下，发展语音声学和空气声学领域的专门知识 探讨影响腭咽闭合不全(VPI)所致语音障碍的声源机制。 专业发展计划包括一套结构化的课程，包括课程作业、研讨会、研讨会和 在指导和咨询团队的监督下进行个人学习。指导委员会包括 由在语音和语音的声学建模方面具有专业知识的知名研究人员组成的多学科团队 障碍，语言空气动力学，空气声学，医学成像技术，和临床管理 VPI。研究计划涉及特定的目标，旨在解决以下方面的知识差距 腭咽闭合口大小与VPI和言语严重程度之间缺乏相关性 扭曲。这项研究将以两个假设为指导：1)气流引起的声音特性将会降低 由于腭咽闭合开口的大小增加；2)由于共振而产生的声音特征将增加 随着腭咽闭合开口的大小增加。该公司提供的培训和研究经验 获奖将使候选人能够在VPI的临床领域成功地担任独立研究员 还有颅面畸形。

Project Summary The goal of this K25 Mentored Quantitative Research Career Development Award is to enable the candidate to develop expertise in the areas of acoustics and aeroacoustics of speech, in the context of a research plan that investigates sound source mechanisms that affect speech disorders due to velopharyngeal insufficiency (VPI). The professional development plan involves a structured curriculum of coursework, workshops, seminars, and individual study under the supervision of a mentorship and advisory team. The mentorship committee includes multidisciplinary team of established researchers with expertise in acoustic modeling of speech and speech disorders, aerodynamics of speech, aeroacoustics, medical imaging techniques, and clinical management of VPI. The research plan involves specific aims that have been designed to address the gap in knowledge for the lack of correlation between the size of the velopharyngeal opening with VPI and the severity of speech distortion. The research will be guided by two hypotheses: 1) sound characteristics due to airflow will decrease as the size of the velopharyngeal opening is increased; 2) sound characteristics due to resonance will increase as the size of the velopharyngeal opening is increased. The training and research experience provided by this award will enable the candidate to successfully bear as an independent researcher in the clinical areas of VPI and craniofacial anomalies.