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中文摘要
翻译
项目总结 这项研究将调查视觉信息在前额叶皮质中是如何呈现的,这是大脑中涉及的区域 具有较高的认知功能,训练前后要执行一项工作记忆任务。猴子将会是 接受认知任务培训,要求他们观察和记忆具有多种视觉刺激的显示。 随着训练的进行,用微电极阵列进行的神经生理学记录将使我们能够 确定确定预期行为改善的神经元激活模式 性能和工作内存容量。这些实验将揭示这些变化的本质 在训练期间放置在前额叶皮质,以执行工作记忆任务。
英文摘要
PROJECT SUMMARY The study will investigate how visual information is represented in the prefrontal cortex, the brain area involved with higher cognitive functions, before and after training to perform a working memory tasks. Monkeys will be trained in cognitive tasks that require them to observe and remember displays with multiple visual stimuli. Neurophysiological recordings with an array of microelectrodes as training progresses will allow us to determine the patterns of neuronal activation that determine the expected improvement in behavioral performance and working memory capacity. The experiments will uncover the nature of changes that take place in the prefrontal cortex during training to perform a working memory task.
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PREFRONTAL CIRCUITS OF WORKING MEMORY
  • 批准号:
    10446082
  • 项目类别:
  • 资助金额:
    $72.42万
  • 财政年份:
    2022
  • 负责人:
    CHRISTOS CONSTANTINIDIS
  • 依托单位:
Neurophysiology of cognitive development and response inhibition
  • 批准号:
    10470316
  • 项目类别:
  • 资助金额:
    $43.31万
  • 财政年份:
    2018
  • 负责人:
    CHRISTOS CONSTANTINIDIS
  • 依托单位:
Neurophysiology of cognitive development and response inhibition
  • 批准号:
    10399718
  • 项目类别:
  • 资助金额:
    $38.06万
  • 财政年份:
    2018
  • 负责人:
    CHRISTOS CONSTANTINIDIS
  • 依托单位:
Neurophysiology of Working Memory Maturation in Adolescence
  • 批准号:
    10408340
  • 项目类别:
  • 资助金额:
    $51.45万
  • 财政年份:
    2018
  • 负责人:
    CHRISTOS CONSTANTINIDIS
  • 依托单位:
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