Neurophysiological effects of training in visual cognitive tasks
Neurophysiological effects of training in visual cognitive tasks
批准号:
10403363
负责人:
CHRISTOS CONSTANTINIDIS
金额:
$45.44万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-06-03 至 2023-05-31
关键词:
AddressAdultAge-associated memory impairmentAlzheimer&aposs DiseaseAreaAwardBasic ScienceBehavioralBrainCognitive deficitsCognitive remediationComplexData SetDiseaseEducational InterventionGoalsImpaired cognitionIndividualInformation StorageIntelligenceInterventionKnowledgeLanguageLiquid substanceLiteratureLocationMagicMaintenanceMemoryMental disordersMicroelectrodesMindModelingMonkeysNatureNeurobehavioral ManifestationsNeuronsNoisePerformancePeriodicityPrefrontal CortexPsychological TransferResolutionRoleSensoryShort-Term MemorySiteStimulusStrokeTask PerformancesTestingTheoretical StudiesTrainingTraumatic Brain InjuryVisualadjudicatebasecognitive functioncognitive taskcognitive trainingdesignexperimental studyextrastriate visual cortexfunctional restorationimprovedinsightneural correlateneuronal patterningneurophysiologynonhuman primatenormal agingrecruitrelating to nervous systemtraittreatment strategyvisual informationvisual stimulus
中文摘要
项目总结
这项研究将调查视觉信息在前额叶皮质中是如何呈现的,这是大脑中涉及的区域
具有较高的认知功能,训练前后要执行一项工作记忆任务。猴子将会是
接受认知任务培训,要求他们观察和记忆具有多种视觉刺激的显示。
随着训练的进行,用微电极阵列进行的神经生理学记录将使我们能够
确定确定预期行为改善的神经元激活模式
性能和工作内存容量。这些实验将揭示这些变化的本质
在训练期间放置在前额叶皮质,以执行工作记忆任务。
英文摘要
PROJECT SUMMARY
The study will investigate how visual information is represented in the prefrontal cortex, the brain area involved
with higher cognitive functions, before and after training to perform a working memory tasks. Monkeys will be
trained in cognitive tasks that require them to observe and remember displays with multiple visual stimuli.
Neurophysiological recordings with an array of microelectrodes as training progresses will allow us to
determine the patterns of neuronal activation that determine the expected improvement in behavioral
performance and working memory capacity. The experiments will uncover the nature of changes that take
place in the prefrontal cortex during training to perform a working memory task.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
PREFRONTAL CIRCUITS OF WORKING MEMORY
-
批准号:10446082
-
项目类别:
-
资助金额:$72.42万
-
财政年份:2022
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of cognitive development and response inhibition
-
批准号:10470316
-
项目类别:
-
资助金额:$43.31万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of cognitive development and response inhibition
-
批准号:10399718
-
项目类别:
-
资助金额:$38.06万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Working Memory Maturation in Adolescence
-
批准号:10408340
-
项目类别:
-
资助金额:$51.45万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Working Memory Maturation in Adolescence
-
批准号:10455645
-
项目类别:
-
资助金额:$45.41万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of cognitive development and response inhibition
-
批准号:9923735
-
项目类别:
-
资助金额:$44.62万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of cognitive development and response inhibition
-
批准号:9750807
-
项目类别:
-
资助金额:$40.22万
-
财政年份:2018
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Prefrontal Cortical Development
-
批准号:8339479
-
项目类别:
-
资助金额:$36.99万
-
财政年份:2009
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Prefrontal Cortical Development
-
批准号:7936269
-
项目类别:
-
资助金额:$27.04万
-
财政年份:2009
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Prefrontal Cortical Development
-
批准号:8517189
-
项目类别:
-
资助金额:$34.09万
-
财政年份:2009
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Prefrontal Cortical Development
-
批准号:7742804
-
项目类别:
-
资助金额:$31.6万
-
财政年份:2009
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Neurophysiology of Prefrontal Cortical Development
-
批准号:8082729
-
项目类别:
-
资助金额:$25.77万
-
财政年份:2009
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Cortical Circuit Basis of Visual Spatial Processing
-
批准号:8968551
-
项目类别:
-
资助金额:$38.44万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CHOLINERGIC INFLUENCES ON PREFRONTAL CORTICAL ACTIVITY DURING COGNITIVE FUNCTION
-
批准号:7452035
-
项目类别:
-
资助金额:$23.35万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CORTICAL CIRCUIT BASIS OF VISUAL SPATIAL PROCESSING
-
批准号:7524381
-
项目类别:
-
资助金额:$28.4万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CORTICAL CIRCUIT BASIS OF VISUAL SPATIAL PROCESSING
-
批准号:7681027
-
项目类别:
-
资助金额:$28.4万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CHOLINERGIC INFLUENCES ON PREFRONTAL CORTICAL ACTIVITY DURING COGNITIVE FUNCTION
-
批准号:7618786
-
项目类别:
-
资助金额:$18.45万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CORTICAL CIRCUIT BASIS OF VISUAL SPATIAL PROCESSING
-
批准号:7920041
-
项目类别:
-
资助金额:$29.3万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
CORTICAL CIRCUIT BASIS OF VISUAL SPATIAL PROCESSING
-
批准号:8135331
-
项目类别:
-
资助金额:$28.42万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
Cortical Circuit Basis of Visual Spatial Processing
-
批准号:9148178
-
项目类别:
-
资助金额:$38.44万
-
财政年份:2008
-
负责人:CHRISTOS CONSTANTINIDIS
-
依托单位:
海外基金