Administrative Core

行政核心将通过营造科学的环境，使整体大于局部 这促进了CORT的总体目标：增进对系统性硬化症(SSC)的理解 发病机制，以确定疾病的新生物标志物，并为SSc患者发现新的治疗方法。 Robert Lafyatis博士将作为项目主任领导CORT并担任执行委员会主席，执行委员会由以下成员组成 每个项目和核心的主任和副主任与Robyn Domsic博士的计划 副主任。奥利弗·埃克尔伯格博士，皮特大学基础和翻译科学副主席(项目2，PI)； 肺血管生物和医学中心(项目3，PI)主任Stephen Chan博士和Dr。 系统免疫学中心(核心C，PI)主任Harinder Singh将提供额外的领导 执行委员会的经验。行政核心将组织执行委员会会议 每隔一个月作为讨论行政组织的时间，但更重要的是 调查人员之间进行科学交流的时间到了。行政核心将汇集一位经验丰富的 由内科科学家组成的外部咨询委员会，致力于CORT项目和 核心：SSc皮肤病、间质性肺疾病、肺动脉高压、生物标记物、系统生物学 和临床结果。该委员会将每年审查每个项目和核心，批评进展，探索 障碍，并为新的科学方向提供建议。CORT管理核心将管理 预算，安排执行委员会和咨询委员会的会议，协助CORT主任准备 报告，管理网站，征求和组织对试点和可行性建议的审查，并安排 丰富研讨会。该中心将组织强有力的沟通所需的结构，以便 推进组成该中心的跨学科小组的科学研究。行政核心将提供 通过特邀演讲者为CORT调查人员提供丰富的机会；征集和组织咨询 委员会对试点和可行性补助金的评估，对象是年轻、早期和少数群体调查人员； 并为少数族裔、年轻的早期调查人员组织辅导

The Administrative Core will enable the whole to be greater than the parts by fostering a scientific environment that promotes the overall CORT objectives: advancing understanding of systemic sclerosis (SSc) pathogenesis, to identifying new biomarkers of disease, and discovering novel therapies for patients with SSc. Dr. Robert Lafyatis will lead the CORT as Program Director and chair the Executive Committee, composed of the directors and associate directors of each of the projects and cores with Dr. Robyn Domsic the Program Associate Director. Dr. Oliver Eickelberg, U Pitt Vice Chair for Basic and Translational Science (project 2, PI); Dr. Stephen Chan, Director, Center for Pulmonary Vascular Biology and Medicine (project 3, PI); and Dr. Harinder Singh, Director of the Center for Systems Immunology (Core C, PI) will provide additional leadership experience for the Executive Committee. The administrative core will organize Executive Committee meetings every other month that will serve both as a time to discuss administrative organization, but more importantly a time for scientific exchange between investigators. The Administrative Core will assemble a highly-experienced external Advisory Committee composed of physician-scientists, working in the areas of CORT projects and cores: SSc skin disease, interstitial lung disease, pulmonary arterial hypertension, biomarkers, systems biology and clinical outcomes. This committee will annually review each project and core, critiquing progress, probing obstacles, and providing advice for new scientific directions. The CORT Administrative Core will manage budgets, arrange meetings of the Executive and Advisory committees, assist the CORT director in preparing reports, manage the website, solicit and organize review of Pilot and Feasibility proposals, and arrange enrichment seminars. The Center will organize the structures needed for robust communication in order to advance the science of the interdisciplinary groups composing the Center. The Administrative Core will provide enrichment opportunities for CORT investigators through invited speakers; solicit and organize Advisory Committee evaluation of Pilot and Feasibility Grants, targeting young, early stage and minority investigators; and organize mentoring for minority, young, early stage investigators