Training in Investigative Dermatology

项目总结 耶鲁大学皮肤科的这份T32竞争续签申请提议继续其 在皮肤科学术领域培养未来领导者方面有良好的记录。在32名实习生中， 在过去15年的资助中获得此T32计划的支持，并已完成 分专业和/或研究培训，22人(60%)目前处于全职学术职位，13人 积极从事实质性的基础和/或临床研究，其他9人是全职临床医生- 耶鲁大学、哈佛大学、斯坦福大学、西北大学和职业卫生与公众服务部的教育工作者。重点将继续放在这个项目上 发展MD和MD/PhD皮肤科医生的研究和批判性思维技能，尽管是博士 对翻译和分子领域有重大贡献的候选人 皮肤生物学也将被考虑。我们还建议在下一个时期利用 根据我校教师在培养医学博士和博士后研究生方面的经验 在全国范围内推广T32培训计划，包括我们自己的。目前确定的培训人员 这次更新由32名个人组成，他们在皮肤生物学和 有丰富的以前的指导经验。27个是由R01资助的“初级导师/P受体”(8个有教员 皮肤科就诊19人，其他9个科室就诊19人)。一切都已确定 指导和进行尖端研究，共同涵盖了相当大一部分细胞和 分子生物学。然而，受训者并不局限于这些目前被确定为研究导师的人 项目导师；强烈鼓励他们在整个大学范围内广泛寻找以下导师 实验室将为他们提供进一步发展和完善他们的研究和 批判性思维技能。作为主要导师的资格包括当前R01级别的资金，a 记录以前作为成功导师的跟踪记录，并得到该计划执行人员的批准 委员会审议阶段。因为我们认为它最有利于学员智力独立的发展 并将新的科学技能引入皮肤科，大量接触到杰出的 我们部门以外的调查人员将继续受到重视。与过去的供资时期一样，每个 学员将有两位导师，一位在皮肤科，一位在皮肤科之外。通常，主要导师/PI是 BASE在系外，皮肤科教研室副导师担任额外的 监督实习生的进展，以帮助确保她/他的职业发展轨迹保持在正轨上。17皮肤科 教职员工已被指定为潜在的“二级导师/顾问”，包括医生- 科学家以及那些主要以临床为导向或尚未完全确定他们的指标的科学家 研究项目。已有4人被确认为初级教员，他们有能力获得 经过同行审查的供资和在下一个供资周期内成为主要导师的突出潜力。

PROJECT SUMMARY This T32 competitive renewal application from the Yale Department of Dermatology proposes to continue its strong track record of training future leaders in academic dermatology. Of the 32 trainees who were supported by this T32 program during the past 15 years of funding and who have completed their subspecialty and/or research training, 22 (>60%) are currently in full-time academic positions, and 13 are actively engaged in substantive basic and/or clinical investigation, while 9 others are full-time clinician- educators at Yale, Harvard, Stanford, Northwestern, and OSHU. Emphasis will be maintained on this program developing the research and critical thinking skills of MD and MD/PhD dermatologists, although PhD candidates with significant potential to make substantive contributions to translational and molecular cutaneous biology will also be sought out for consideration. We also propose in the next period to capitalize upon the experience of our faculty in training talented MD/PhD and PhD pre-doctoral students who now populate T32 training programs across the country, including our own. The currently identified training faculty for this renewal consists of thirty-two individuals with broad-ranging expertise in cutaneous biology and substantive previous mentoring experience. 27 are R01-funded “Primary Mentors/Preceptors” (8 with faculty appointments in Dermatology and 19 with appointments in nine other departments). All are established mentors and conducting cutting-edge research collectively encompassing a substantial portion of cellular and molecular biology. However, trainees are not restricted to these currently identified mentors as research project preceptors; they are strongly encouraged to look broadly throughout the university for mentors whose laboratories would provide them with the best opportunities to further develop and refine their research and critical thinking skills. Qualifications for being a primary mentor include current R01 level sfunding, a documented previous track record as a successful mentor, and approval by this program's Executive Committee. Because we consider it most conducive to the trainees' development of intellectual independence and to the introduction of new scientific skills into dermatology, substantial exposure to outstanding investigators outside our own department will continue to be emphasized. As in past funding periods, each trainee will have two mentors, one inside and one outside of Dermatology. Typically, the Primary Mentor/PI is based is outside the department, and the Dermatology faculty secondary advisor serves as an additional monitor of the trainee's progress to help ensure that her/his career trajectory stays on course. 17 Dermatology faculty members have been designated as potenital “Secondary Mentors/Advisors” including physician- scientists as well as those that are principally clinically oriented or have yet to fully establish their indendent research programs. 4 individuals have been identified as junior faculty with demonstrated abilities to obtain peer-reviewed funding and outstanding potential to become primary mentors within the next funding cycle.