Postdoctoral Research Training in Alzheimer's Disease and Related Neurodegenerative Disorders

这是一项更新纽约大学格罗斯曼医学院高级博士后培训计划的建议，该计划专注于阿尔茨海默病和相关的神经退行性疾病。迫切需要培训早期职业科学家，他们将调查阿尔茨海默病和相关的神经退行性疾病，开发新的干预措施，并将这些发现从实验室转化为床边，从床边转化为社区。该计划将继续被安置在认知神经病学中心，这是一个旨在促进合作研究的跨部门，多学科计划，有37名教师担任导师。该计划的目标是赋予具有不同科学背景的学员必要的技能，多学科方法和严格的方法，以推进阿尔茨海默病和相关神经退行性疾病领域。这一更新申请通过任命杰出的认知神经学临床医生-科学家研究人员来扩展我们目前的培训计划。我们将在我们以前的培训计划的基础上，从合格的MD，MD/PhD和PhD申请人中任命三名博士后学员和一名认知神经学研究员。根据NIH对博士后研究培训的建议，学员将被任命两年，并将在随后的几年中继续获得指导和职业发展支持。该计划的目标是培养这些研究员将通过量身定制的课程，包括严格的研究技术和定量分析，加强导师，在基础概念教学法，磨练科学沟通技能和职业规划的培训来实现。该培训计划使博士后研究员能够为现代研究的密切合作和跨学科性质做好准备，提供：（a）阿尔茨海默病和相关神经退行性疾病领域的高质量科学培训，临床方法，统计分析和严格的实验设计;（B）加强指导，帮助受训者在未来的科学事业中取得进步，（c）培训在学术研究中取得成功所必需的专业技能，包括批判性阅读、撰写资助论文、口头报告、领导力、管理和网络。在阿尔茨海默病和相关神经退行性疾病方面具有专业知识的下一代研究和临床科学家的培训是，并将继续是美国未来多年的公共卫生优先事项。我们的合作T32计划支持这些早期的科学家，因为他们在这个关键领域推出了独立和成功的职业生涯。

This is a proposal to renew an advanced postdoctoral training program focused on Alzheimer’s disease and related neurodegenerative disorders at NYU Grossman School of Medicine. There is a critical need to train early career scientists who will investigate Alzheimer’s disease and related neurodegenerative disorders, develop new interventions, and translate these findings from bench to bedside and from bedside to community. The program will continue to be housed in the Center for Cognitive Neurology, an extra-departmental, multidisciplinary program designed to foster collaborative research, with 37 faculty members serving as mentors. The goal of the program is to endow trainees with diverse scientific backgrounds with the necessary skills, multidisciplinary approaches, and rigorous methodologies to advance the field of Alzheimer’s disease and related neurodegenerative disorders. This renewal application expands our current training program by appointing exceptional cognitive neurology clinician-scientist researchers. We will build on our previous training program by appointing three postdoctoral trainees and one cognitive neurology fellow from a well-qualified pool of MD, MD/PhD, and PhD applicants. As per the NIH recommendation for postdoctoral research training, the trainees will be appointed for two years and will continue to receive mentoring and career development support in subsequent years. The program's goals to train these fellows will be accomplished through a tailored curriculum that includes training in rigorous research techniques and quantitative analysis, enhanced mentorship, didactics in foundational concepts, honing science communication skills, and career planning. This training program enables postdoctoral fellows to prepare for the intensely collaborative and interdisciplinary nature of modern research by providing: (a) high-quality scientific training in the area of Alzheimer’s disease and related neurodegenerative disorders, clinical approaches, statistical analyses, and rigorous experimental design; (b) enhanced mentoring that aids trainees’ progress toward future careers in science, and (c) training in the professional skills that are necessary for success in academic research, including critical reading, grant writing, oral presentation, leadership, management, and networking. The training of the next generation of research and clinician scientists with expertise in Alzheimer’s disease and related neurodegenerative disorders is, and will remain, a public health priority in the United States for many years to come. Our collaborative T32 program supports these early scientists as they launch their independent and successful careers in this critical field.