Medical Scientist National Research Service Award

项目摘要 医学科学家培训计划（MSTP）致力于培养下一代学者， 生物医学科学的领导者，为学生提供最好的资源， 芝加哥大学。芝加哥独特的跨学科方法鼓励学生探索他们的 医学和研究兴趣在医学，生物学，社会科学和 物理科学芝加哥大学是最早获得MSTP联邦资助的学校之一。 目前，我们是在我们的第50年，并已毕业290医生科学家。我们的受训者 为我们理解生物学和人类疾病做出了重要贡献， 《自然》、《科学》、《细胞》和其他高影响力期刊。我们的毕业生已经领导了重要的 部门和学术单位，包括加州大学旧金山分校，斯坦福大学，哈佛和印第安纳州的MSTP。我们的四 受训人员被选入国家科学院。在本培训补助金期间 （2012-2016），我们已经毕业了33名学生，他们都发表了大量的工作。 值得注意的是，我们目前的16名学生中有13名（81%）在F30申请中取得了成功。这个水平 在保持7.9年毕业时间和5年毕业时间的同时， 损耗率为2.5%。从任何角度来看，我们的项目、学员和毕业生都是成功的。目前64 来自全国各地的个人参加了该方案，其中50%为妇女，22%为 统一资源管理系统。我们是一个多元化和平衡的国家卓越的学术计划。我们也是一个高度 具有竞争力的计划，五年平均入学指标为3.81 GPA和98% MCAT，并获得入学资格 从2280名五年申请人中获得2.1%的比例。我们要求更新我们目前的22个插槽。 这种程度的支持，加上芝加哥大学的大量和持续支持， 生物科学部，将确保至少10%的总传入普利兹克医学院类 都被训练成了医学科学家相对于我们的机构支持，要求NIH的投资是 这是合理的，只占我们预期预算的24%。

PROJECT SUMMARY The Medical Scientist Training Program (MSTP) is committed to training the next generation of scholars and leaders in the biomedical sciences by providing students with access to the very best resources of the University of Chicago. Chicago's distinctive interdisciplinary approach encourages students to explore their medical and research interests in the broadest possible terms in medicine, biology, the social sciences and the physical sciences. The University of Chicago was among the first schools to obtain MSTP federal funding. Currently, we are in our 50th year and have graduated 290 physician scientists. Our trainees have made many fundamental contributions to our understanding of biology and human disease resulting in numerous papers in Nature, Science, Cell, and other high-impact journals. Our graduates have gone on to lead important departments and academic units including the MSTPs at UCSF, Stanford, Harvard and Indiana. Four of our trainees have been elected to the National Academy of Sciences. During the current training grant period (2012-2016), we have graduated 33 students all of whom have published substantial bodies of work. Remarkably, 13 of 16 of our current students (81%) have been successful in their F30 applications. This level of accomplishment has been obtained while maintaining a time to graduation of 7.9 years and a five-year attrition rate of 2.5%. By any metric, our program, trainees and graduates are successful. Currently 64 individuals, from all over the country, are enrolled in the program of which 50% are women and 22% are URMs. We are a diverse and balanced national academic program of excellence. We are also a highly competitive program with five-year average entering metrics of 3.81 GPA and 98% MCAT with a matriculation rate of 2.1% from a five-year applicant pool of 2280. We are requesting that our current 22 slots be renewed. This level of support, in conjunction with substantial and ongoing support from the University of Chicago Biological Sciences Division, will ensure that at least 10% of the total incoming Pritzker Medical School Class is trained as physician scientists. Relative to our institutional support, the requested NIH investment is reasonable, constituting only 24% of our anticipated budget.