Administrative Core 1

管理核心1：项目总结/摘要 在SPORE框架内，行政核心（核心1）将负责纳入 将SPORE研究人员的不同科学学科整合为高度集成的跨学科方法 专注于实现卓越的转化黑色素瘤研究，对护理产生重大影响 与这种疾病作斗争的病人。该小组的主要目标是确保成功的持续监督 并通过专家协调所有项目、核心项目以及发展和职业提升计划 指导财务管理、集中沟通和所有活动的一般管理。这 核心将由三位杰出的科学家和公认的导师领导，他们目前拥有高级别的 在MD安德森的行政，研究和/或临床任命，并拥有数十年的组合 领导经验：帕特里克胡博士，伊丽莎白格林和杰弗里E。李你 行政核心的具体职责包括： ·遵守所有机构、联邦和NIH/NCI法规和要求。 ·与NCI项目官员和其他NCI工作人员进行沟通和协商，包括准备 所有要求的报告、出版物和其他要求的通信。 ·与生物统计学和 生物信息学核心（核心3）。 ·优化临床试验工作，包括监测和加强相关的累积进展 通过临床试验管理资源（由Hwu博士和 李先生）住在这个行政核心内。 ·维持财政和预算责任，包括实施SPORE灵活性 通过持续评估计划进展情况和供资理由，酌情选择 分配/再分配。 ·召开所有必要的会议，包括执行委员会、内部和外部咨询委员会 委员会（IAB/EAB），科学会议，研究会议，讲座和研讨会，包括 安排、编制和分发会议材料，并酌情记录会议记录。 ·协调和资助患者维权活动。 ·制定和监测在这方面征聘和保留妇女和少数民族的政策 程序. ·与其他SPORE站点协调，以启动和加强合作研究工作， 赞助一年一度的皮肤癌会议，并寻求高潜力的发展机会 研究计划（DRP）和职业提升计划（CEP）的申请， 合作调查员。

Adminstrative Core 1: Project Summary/Abstract Within the SPORE framework, the Administrative Core (Core 1) will be responsible for incorporating the diverse scientific disciplines of the SPORE investigators into a highly integrated, interdisciplinary approach focused on achieving excellence in translational melanoma research towards a significant impact on the care of patients battling this disease. The primary goal of this group is to assure the successful continued oversight and coordination of all projects, cores, and developmental and career enhancement programs through expert guidance in fiscal management, centralized communication, and general administration for all activities. This core will be led by three outstanding scientists and well-established mentors who currently hold high-level administrative, research, and/or clinical appointments at MD Anderson and possess decades of combined leadership experience: Drs. Patrick Hwu, Elizabeth Grimm, and Jeffrey E. Lee. Specific responsibilities of the Administrative Core include the following: · Compliance with all institutional, federal, and NIH/NCI regulations and requirements. · Communication and consultation with the NCI project officer and other NCI staff, including preparation of all required reports, publications, and other requested communications. · Monitoring data quality control and assurance activities in conjunction with the Biostatistics and Bioinformatics Core (Core 3). · Optimization of clinical trial efforts, including monitoring and enhancing accrual progress of related SPORE clinical trials, through the Clinical Trials Management Resource (co-directed by Dr. Hwu and Lee) housed within this Administrative Core. · Maintenance of fiscal and budgetary responsibilities, including implementing the SPORE flexibility option as appropriate through ongoing assessments of program progress and justifications for funding allocations/reallocations. · Convening all necessary meetings, including the Executive Committee, Internal and External Advisory Boards (IAB/EAB), scientific meetings, research meetings, lectures, and symposia, including scheduling, development and distribution of meeting materials, and recording minutes as appropriate. · Coordination and funding of Patient Advocate activities. · Establishment and monitoring of policies for recruitment and retention of women and minorities in this program. · Coordination with other SPORE sites to initiate and enhance collaborative research efforts, co- sponsor a yearly Skin Cancer conference, and pursue opportunities for high potential Developmental Research Program (DRP) and Career Enhancement Program (CEP) applications from collaborating investigators.