High potency food grade growth factor mimics for low cost cultivated meat manufacture

人造肉有望通过提供一种更道德和更绿色的动物产品替代品，同时保持相同的味道和质地，从而彻底改变食品行业。然而，这些产品由于生产的技术复杂性，特别是制造中使用的材料成本高而受到阻碍。据估计，成本需要降低99%或更多。这些成本的主要贡献者是生产中使用的蛋白质，这些蛋白质提供刺激生长的生物线索，并确保生产出正确类型的肉细胞。除非这些蛋白质的成本可以降低99%或更多，否则该行业在经济上是不可行的。MarraBio已经开发出一种全新的方法来制造目前使用的蛋白质的替代品。它的材料可以大量生产，成本将使养殖肉类在经济上可行。到目前为止，MarraBio已经生产了“研究级”版本的产品，并有初步证据表明它们将满足该行业的需求。在该项目中，MarraBio将证明这些产品可以大规模生产，其质量将满足其在养殖肉类生产中使用所需的监管要求。如果成功的话，到项目结束时，我们将能够在这个快速增长的市场上推出我们的产品。为了实现这些目标，MarraBio与工艺创新中心（CPI）和Aelius Biotech合作。CPI是蛋白质制造和分析领域的领导者，将协助MarraBio完善其制造技术，以严格控制产品质量和效价。Aelius Biotech开发了一种肠道模型，可以预测摄入的物质将如何影响消化系统。他们的参与将使MarraBio能够测试他们的产品是如何在摄入时处理的-这是一个关键的安全步骤-同时允许Aelius进一步开发他们的技术以满足该行业的需求。所有参与者都位于英格兰东北部，他们的合作将支持该地区快速增长的人工养殖肉类行业。该项目的成果将对经济生产人工养殖肉类的能力产生重大影响。这将提供一种高质量、有效的产品，简化并降低养殖肉类生产的成本。

Cultivated meat promises to revolutionize the food industry by providing a more ethical and greener alternative to animal products, whilst retaining the same taste and texture. However, these products are being held back by the technical complexity of production and, in particular, the high cost of materials used in their manufacture. It is estimated that costs need to be reduced by 99% or more.A major contributor to these costs are the proteins used in production which supply biological cues to stimulate growth and ensure that the right type of meat cells are produced. Unless the cost of these proteins can be reduced by 99% or more, the sector will not be economically viable.MarraBio has have developed a radically new way to make alternatives to the proteins currently used. Its materials can be made in very large quantities, and at a cost which will make cultivated meat economically viable. So far, MarraBio has produced "research grade" versions of the products and have preliminary evidence that they will meet the needs of the sector. In the project, MarraBio will demonstrate that the products can be produced at scale and at a quality where they will meet the regulatory requirements needed for their use in cultivated meat production. If successful, by the end of the project we will be in a position to launch our products on this rapidly growing market.To achieve these aims MarraBio are partnering with the Centre for Process Innovation (CPI) and Aelius Biotech. CPI is a leader in protein manufacturing and analysis and will assist MarraBio in refining its manufacturing techniques to provide tight control over product quality and potency. Aelius Biotech have developed a model of the gut that predicts how ingested substances will affect the digestive system. Their involvement will allow MarraBio to test how their products are processed on ingestion - a critical safety step -- whilst allowing Aelius to further develop their technology towards the needs of this sector. With all participants based in North East England, their collaboration will support the rapidly growing cultivated meat sector in the region.The outcomes of the project will have a significant impact on the ability to economically produce cultivated meat. This will provide a high quality, potent product that simplifies and reduces the cost of cultivated meat manufacture.