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中文摘要
翻译
综述-显微镜和组织处理核心 显微镜和组织处理核心提供设备、专业知识、用品和技术服务 为了满足加州大学戴维斯分校NEI资助的研究人员的常规和高级显微镜需求, 强调细胞生物学方法。昂贵的设备,如低温恒温器、超微切割机、通风 埋入烤箱,用于催化LR等树脂聚合的冷藏UV聚合装置 白色、冷冻替代系统和危险试剂,如EM和 用于LM的溶剂和着色剂都以更具成本效益的方式提供核心服务。就像许多人 这些试剂和方法涉及危险化合物,同样具有更高的成本效益 将危险废物处理限制在一个单元内。虽然大多数调查人员都是最专业的 精密类型的光学显微镜,很少有人有进行光学和电子显微镜的知识 嵌入的标本。拥有一名训练有素的单一员工会产生更好的结果,从而提高工作效率 举止。
英文摘要
SUMMARY – MICROSCOPY AND TISSUE PROCESSING CORE The Microscopy and Tissue Processing Core provides the equipment, expertise, supplies and technical service to meet both the routine and advanced microscopy needs of NEI-funded investigators at UC Davis who emphasize cell biological approaches. Expensive devices such as cryostats, ultramicrotomes, ventilated embedding ovens, refrigerated UV polymerization units for catalyzing the polymerization of resins such as LR White, and freeze substitution systems, and hazardous reagents such as the heavy metal salts for EM and solvents and stains for LM, are all provided in a more cost-effective manner with a Core service. As many of these reagents and processes involve hazardous compounds, it is similarly more cost effective to have hazardous waste processing confined to a single unit. While most investigators are expert in the most sophisticated types of light microscopy, very few have the knowledge to conduct light and electron microscopy of embedded specimens. Having a single, well-trained staff person produces better results in a more efficient manner.
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Regulation of Lens Fiber Cell Structure and Function by Post Translational Modification of Intermediate Filaments
  • 批准号:
    9900012
  • 项目类别:
  • 资助金额:
    $39.25万
  • 财政年份:
    2017
  • 负责人:
    PAUL Gillespie FITZGERALD
  • 依托单位:
Regulation of Lens Fiber Cell Structure and Function by Post Translational Modification of Intermediate Filaments
  • 批准号:
    9217353
  • 项目类别:
  • 资助金额:
    $39.93万
  • 财政年份:
    2017
  • 负责人:
    PAUL Gillespie FITZGERALD
  • 依托单位:
Non Fiber Cell Functions for the Beaded Filament Proteins
  • 批准号:
    8747592
  • 项目类别:
  • 资助金额:
    $23.33万
  • 财政年份:
    2014
  • 负责人:
    PAUL Gillespie FITZGERALD
  • 依托单位:
SDSL-EPR STUDY OF INTERMEDIATE FILAMENT STRUCTURE
  • 批准号:
    7207948
  • 项目类别:
  • 资助金额:
    $29.49万
  • 财政年份:
    2006
  • 负责人:
    PAUL Gillespie FITZGERALD
  • 依托单位:
海外基金