The Development of Eating Behavior in Infancy: Associations with Behavior, Diet, and Growth to Age 6 years

项目总结 饮食行为与饮食质量和体重增加密切相关。考虑到进食的相关性 儿童和成人的健康行为，对这些行为的发展知之甚少 从婴儿期开始的行为，及其持续(或间断)到童年的行为。进食行为可以是 通过严格测量暴露在不同刺激下的行为在婴儿期的表型 仔细的实验对照，尽管在R01HD084163之前没有研究表明多次进食 在单个纵向婴儿队列中的客观行为。饮食行为在婴儿期之间可能是可以改变的 和儿童早期，潜在地改变了与未来饮食质量或体重增加的任何联系。干预措施 促进适应性母亲喂养做法在降低肥胖风险方面一直是有效的。干预 根据个别儿童的特点进行量身定做，可以进一步加强效果。识别 一项观察性研究中仔细分型的儿童进食行为与母亲喂养行为的相互作用 队列研究是迈向未来量身定制干预发展的重要的第一步。拟议中的工作 将首次检查广泛表型饮食行为的连续性(或间断性) 婴儿期，根据新的客观测量和产妇报告，到5岁。这项工作将是第一次 时间，测试母亲的喂养习惯和婴儿的饮食行为是否相互作用来预测儿童的饮食 5岁时的行为，以及6岁时的饮食质量和BMI。美国广播公司的婴儿研究 (R01HD084163，7/1/15-06/30/20)及其附属资助研究使用新的行为方案 在2周龄、2、4、6、9和9岁时，表型进食行为和母亲纵向喂养实践 在286名婴儿的队列中，12个月。目前的申请计划在以下地点对其中200名儿童进行跟进 5岁和6岁：目标1：测试儿童之间的交叉滞后联系 婴儿期和5岁时的饮食行为和母亲喂养习惯。我们假设那个孩子 婴儿期的饮食行为预测5岁儿童的饮食行为，婴儿期的母亲喂养行为 预测母亲在5岁时的喂养行为，婴儿时期的饮食行为预测母亲的喂养 5岁时的喂养习惯和婴儿时期的母婴喂养习惯预测了5岁时的儿童进食行为。目标2： 检验在婴儿期测量的饮食行为有直接和间接(通过吃)的假设 5岁时的行为)与6岁时的饮食质量和BMI相关。目标3：测试 假设婴儿时期的母亲喂养行为与婴儿饮食行为之间存在适度的关联 5岁时的饮食行为，以及5岁时的母亲喂养做法对饮食的影响 婴儿期行为与6岁时的饮食质量和BMI，以及与饮食的适度关联 5岁时的行为与饮食质量和6岁时的BMI有关。

PROJECT SUMMARY Eating behaviors are robustly associated with dietary quality and weight gain. Given the relevance of eating behaviors to health in children and adults, remarkably little is known regarding the development of these behaviors from infancy, and their continuity (or discontinuity) into childhood. Eating behaviors can be phenotyped in infancy through rigorous measurement of behavior following exposure to different stimuli under careful experimental control, though no studies prior to R01HD084163 have phenotyped multiple eating behaviors objectively in a single longitudinal infant cohort. Eating behavior may be modifiable between infancy and early childhood, potentially altering any associations with future dietary quality or weight gain. Interventions that promote adaptive maternal feeding practices have been effective in reducing obesity risk. Intervention effects might be further strengthened by tailoring to characteristics of the individual child. Identifying interactions of carefully phenotyped child eating behavior and maternal feeding practices in an observational cohort study is an important initial step towards future tailored intervention development. The proposed work will examine for the first time the continuity (or discontinuity) of extensively phenotyped eating behaviors in infancy, based on novel objective measures and maternal report, to age 5 years. The work will, for the first time, test whether maternal feeding practices and infant eating behaviors interact to predict child eating behaviors at age 5 years, as well as dietary quality and BMI at age 6 years. The ABC Baby study (R01HD084163, 7/1/15-06/30/20) and its ancillary funded studies used novel behavioral protocols to phenotype eating behavior and maternal feeding practices longitudinally at ages 2 weeks, and 2, 4, 6, 9, and 12 months in a cohort of 286 infants. The current application proposes to follow up with 200 of these children at ages 5 and 6 years to address the following aims: Aim 1: To test the cross-lagged associations between child eating behaviors and maternal feeding practices across infancy and age 5 years. We hypothesize that child eating behaviors in infancy predict child eating behaviors at age 5 years, maternal feeding practices in infancy predict maternal feeding practices at age 5 years, child eating behaviors in infancy predict maternal feeding practices at 5 years, and maternal feeding practices in infancy predict child eating behaviors at 5 years. Aim 2: To test the hypothesis that eating behaviors measured in infancy have direct and indirect (through eating behaviors at age 5 years) associations with dietary quality and BMI at age 6 years. Aim 3: To test the hypotheses that maternal feeding practices in infancy moderate associations of infant eating behaviors with eating behaviors at 5 years, and that maternal feeding practices at 5 years moderate associations of eating behaviors in infancy with dietary quality and BMI at age 6 years, and moderate associations of eating behaviors at age 5 years with dietary quality and BMI at age 6 years.