Annual Cannabinoid Research Society Symposium on the Cannabinoids

项目摘要 大麻素信号传导由大麻素受体CB 1和CB 2及其同源外源性受体组成。 和内源性配体。大麻素信号广泛分布在整个中枢神经系统和外周 并与多种重要的神经生物学过程有关， 稳态、学习和记忆、运动功能、奖励、焦虑和社会功能。此外，使用 大麻在过去十年中有所增加，预计将继续增加， 美国反禁酒运动的发展。弱势群体使用大麻的情况， 在关键时期，如青春期和怀孕，具有不明确的风险，是激烈的焦点， 正在进行的科学调查。与这些日益增长的潜在公共卫生问题相适应， 研究大麻素和与大脑相关的内源性大麻素的基础生物学 发展，功能和病理学正成为公众，政策制定者， 研究人员和医疗保健专业人员。因此，了解大麻素的神经生物学 信号传导可能对躯体和神经系统的生理功能和病理生理学有广泛的影响， 神经精神障碍国际大麻素研究协会（ICRS）是唯一一个 专门传播大麻素科学各方面科学信息的科学会议。 ICRS将于2021年举办第31届年度研讨会，并在该领域取得了无与伦比的成功。 大麻素研究在上一个资助周期，NIH的支持使ICRS能够提供 提供大量差旅支持，以增加学员参加我们年度会议的人数。学生旅行补助金 该计划将用于增加早期大麻素研究人员在ICRS中的参与 关于大麻素的研讨会。一直并将继续特别强调支持 传统上在科学领域代表性不足的个人，包括女性以及美国种族和民族 少数群体除了旅游奖励计划，我们建议提供一个职业发展计划 在每年的ICRS研讨会上，表彰优秀的博士前和博士后学生 在每次研讨会期间进行颁奖，并出版一本印刷形式的摘要书， 将在年度专题讨论会后在国际遥感中心网站上向公众提供。完成这些 目标将继续通过促进出席和鼓励下一代大麻素科学家， 在开放，包容和平等的论坛上展示他们的原创研究，并提供网络 并为大麻素研究各个领域的年轻科学家提供指导机会。

PROJECT SUMMARY Cannabinoid signaling is composed of Cannabinoid receptors CB1 and CB2 and their cognate exogenous and endogenous ligands. Cannabinoid signaling is widely distributed throughout the CNS and periphery and is implicated in a wide variety of important neurobiological processes including regulation of energy homeostasis, learning and memory, motor function, reward, anxiety, and social function. Moreover, use of cannabis has increases over the past decade and is expected to continue to increase in the face of the expanding anti-prohibition movement in the United States. Cannabis use by vulnerable populations and during critical periods, such as adolescence and pregnancy, carry unclear risk and are the focus of intense ongoing scientific investigation. Commensurate with these growing potential public health concerns, research into the fundamental biology of cannabinoids and endogenous cannabinoids related to brain development, function, and pathology are becoming of greater interest to the public, policymakers, researchers and healthcare professionals. Therefore, understanding the neurobiology of cannabinoid signaling could have broad implications for physiological function and the pathophysiology of somatic and neuropsychiatric disorders. The International Cannabinoid Research Society (ICRS) is the only annual scientific meeting devoted to dissemination of scientific information on all aspects of cannabinoid sciences. The ICRS will hold its 31st annual symposium in 2021 and has been an unparalleled success in the field of cannabinoid research. During the previous funding cycle, NIH support has allowed the ICRS to provide substantial travel support to increase trainee attendance at our annual meeting. The student travel grant program will be used to increase the participation of early stage cannabinoid researchers in the ICRS Symposia on the Cannabinoids. Special emphasis has been, and will continue to be, placed on support for individuals traditionally underrepresented in science, including women and U.S. racial and ethnic minorities. In addition to the travel award program, we propose to provide a career development program at each annual ICRS symposium, recognize outstanding predoctoral and postdoctoral student presentations with awards given during each symposium, and publish an abstract book in printed form that will be made available to the public on the ICRS website after the annual symposium. Completion of these aims will continue to invigorate the next generation of cannabinoid scientists by facilitating attendance and presentation of their original research in an open, inclusive, and egalitarian forum and provide networking and mentorship opportunities to young scientists in all areas of cannabinoid research.