HIV self-testing with online supervision for Vietnamese MSM

项目摘要/摘要 在越南，艾滋病病毒在男男性行为的年轻男性中集中流行 那里的艾滋病毒发病率据报道为每100人年5.8人，是世界上最高的地区之一 该地区的事件。对未知者或HIV感染者进行定期(至少每年一次)HIV检测 阴性血清状态对于及时联系艾滋病毒预防服务至关重要，例如风险 减少咨询和艾滋病毒化学预防。在没有意识到现有或 新增HIV感染者，要及时识别，加大联动和启动力度 抗逆转录病毒治疗和护理，以改善疾病前景和预防艾滋病毒 变速箱。然而，结构、后勤和心理社会障碍限制了吸纳和 将越南男男性接触者留在定期艾滋病毒检测中，阻碍了急需的推广 针对这一人群的艾滋病毒预防和治疗服务。这项研究建议使用 将在线艾滋病毒检测(OHT)作为一种替代艾滋病毒检测方式，以增加参与度， 青年男性接触者在艾滋病毒预防、治疗和护理服务中的保留和联系。具体的 本研究提案的目标是：1)确定潜在的障碍和促进因素 在青年男同性恋者中开展OHT；2)制定艾滋病毒的障碍和促进者的经验概况 在基督教青年会中进行测试，包括估计可能参与的基督教青年会的比例 在OHT干预中；以及3)对OHT进行初步评估 干预措施，包括采用一种新的艾滋病毒快速诊断抗体/抗原 通过视频会议与艾滋病毒咨询师进行自我检测，并“实时”自我收集 带集中式艾滋病毒DNA检测的干血点(DBS)技术。快速检测结果 将阅读-集中测试的将通过视频会议交付，随后 在为期12个月的试点中，开展讨论、测试后咨询以及与护理和治疗相联系 学习。特别是后勤问题，对快速艾滋病毒自我检测的担忧，星展银行的自我收集 并将通过视频会议进行实验室测试、阅读或报告结果 评估，以及OHT如何帮助克服现有的一些障碍 以场地为基础的艾滋病毒检测。使用新的艾滋病毒诊断和在线技术，OHT可能是一种 有希望的战略是加强与艾滋病毒预防的接触、保留和联系， 越南基督教青年会的治疗和护理服务。

PROJECT SUMMARY/ABSTRACT There is a concentrated HIV epidemic among young men who have sex with men in Vietnam where HIV incidence was reported to be 5.8 per 100 person-years, one of the highest incidences in the region. Regular (at least annual) HIV testing of YMSM of unknown or HIV negative serostatus is critical for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretroviral treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Vietnamese MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services. The specific aims of this research proposal are 1) To identify potential barriers and facilitators to uptake of OHT among YMSM; 2) to develop an empirical profile of barriers and facilitators to HIV testing among YMSM, including an estimate of the proportion of YMSM likely to participate in an OHT intervention; and 3) To conduct a preliminary assessment of the OHT intervention, including introduction of a new HIV rapid diagnostic antibody/antigen-based self-testing with an HIV counselor through video conferencing, and “real time” self-collected dried blood spot (DBS) technology with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 12-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to venue-based HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Vietnamese YMSM.