ACR Basic & Clinical Research Conference: Disrupting the Genetics of Rheumatology: The Role of Somatic Mutations in Health and Disease

项目摘要-摘要 美国风湿病学会(ACR)一直在努力促进双向 风湿病科学家和研究人员之间的前沿科学信息交流 通过其年度基础和临床研究会议。ACR已成功举办了这次会议 作为单独的计划和作为基础科学和临床研究相结合的计划，以及作为两个方面的计划。 人和虚拟的。每个项目都是在ACR年度会议Conversion的同时举行的。 ACR年度会议ACR Conversion每年吸引10,000至15,000名与会者， 为研究、教育、患者等方面的交流提供论坛的主要机制 护理、执业管理和宣传问题。因为基础和临床研究会议有 与ACR Conversion联合举办，通常作为会前活动，ACR已经能够 吸引著名的科学家和研究人员，否则他们可能不会参加。 2022年，基础和临床研究会议将联合举办，以吸引科学家和研究人员 来自基础、临床和转化性研究社区。会议的暂定名称是 破坏风湿学的遗传学：体细胞突变在健康和疾病中的作用。这 综合方法将侧重于体细胞突变在风湿性疾病发展中的作用。 临床研究会议将集中在体细胞突变关联的遗传流行病学方法 带着疾病。基础研究会议将探讨诸如识别存在和功能的主题 体细胞突变的作用。 会议的组织者包括Jill Norris博士，他是华盛顿大学流行病学系主任兼教授 科罗拉多公共卫生学院；NIAMS厄尔·斯塔特曼研究员彼得·格雷森博士；琳达博士 平木，ACR研究联络委员会，风湿病和科学家科临床医生兼科学家 SickKids研究所遗传学和基因组生物学；ACR委员会Iannis Adamopoloulos博士 研究联络人，以色列贝斯关节炎项目主任兼骨免疫实验室负责人 女执事医学中心；ACR研究委员会主席兼助理Kristine Kuhn博士 科罗拉多大学医学-风湿学教授，科罗拉多大学联合主任 科罗拉多州推进脊柱炎治疗计划。ACR研究委员会专注于 风湿学的研究和研究培训，并鼓励临床和卫生服务研究 组织医疗保健，因为它们可能会影响风湿病患者。

Project Summary-Abstract The American College of Rheumatology (ACR) has been a leader in the effort to facilitate the bidirectional exchange of cutting-edge scientific information between scientists and investigators in rheumatic diseases through its annual Basic and Clinical Research Conferences. The ACR has successfully hosted the conference as separate programs and as a combined basic science and clinical research program, as well as both in- person and virtually. Each program has been held in conjunction with ACR’s annual meeting, Convergence. The ACR annual meeting, ACR Convergence, attracts between 10,000 and 15,000 attendees each year and is the principal mechanism for providing a forum for the exchange of ideas about research, education, patient care, practice management and advocacy issues. Because the Basic and Clinical Research Conferences have been held in conjunction with ACR Convergence, typically as a pre-meeting event, ACR has been able to attract renown scientists and investigators who may otherwise not have attended. For 2022, the Basic and Clinical Research Conference will be held jointly to attract scientists and investigators from both the basic, clinical and translational research communities. The tentative title of the conference is Disrupting the Genetics of Rheumatology: The Role of Somatic Mutations in Health and Disease . This combined approach will focus on the role of somatic mutations in the development rheumatologic diseases. Clinical research sessions will focus on genetic epidemiology approaches for associating somatic mutations with disease. Basic research sessions will explore topics such as identification of the presence and functional role of somatic mutations. The conference organizers include Dr. Jill Norris, Professor and Chair of the Department of Epidemiology at the Colorado School of Public Health; Dr. Peter Grayson, Earl Stadtman Investigator at the NIAMS; Dr. Linda Hiraki, ACR Committee on Research Liaison, Clinician-Scientist in the Division of Rheumatology and Scientist in Genetics & Genome Biology at SickKids Research Institute; Dr. Iannis Adampopoulos, ACR Committee on Research Liaison, Director of the Arthritis Program and Head of Osteoimmunity Laboratory at the Beth Israel Deaconess Medical Center; and Dr. Kristine Kuhn, ACR Committee on Research Chair and Associate Professor of Medicine-Rheumatology at the University of Colorado and the Co-Director of the University of Colorado Program for Advancing Spondyloarthritis Treatment. The ACR Committee on Research focuses on research and research training in rheumatology and encourages clinical and health services research on the organization of medical and health care as they may affect patients with rheumatic diseases.